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Haplotype-specific chromosome painting unveils recombination patterns in the holocentric species Rhynchospora breviuscula H.Pfeiff.

This study uses haplotype-specific chromosome painting to map meiotic recombination patterns in holocentric plants, revealing that recombination events are predominantly located in terminal chromosomal regions.

A cryptic local genetic cluster in Northern France amid the European mosaic of flat oyster lineages revealed by integrating SNP array and whole-genome sequencing

Genetic Association of Somatic Incompatibility and NLR-like Protein Domains in Coprinopsis cinerea

The paper identifies a genetic locus, somA, responsible for allorecognition in Coprinopsis cinerea, revealing a novel mechanism for fungal nonself recognition through polymorphic alleles and purifying selection on an LRR-encoding protein.

The promise of long-read RNA-seq: reducing bias in analyses of allele imbalance

The paper demonstrates that long-read RNA-seq with quality control measures reduces bias in allele counts across four species, improving accuracy in allelic imbalance studies.

Genomic insights into bacterial kidney disease resistance in Arctic charr (Salvelinus alpinus) via a 72k SNP array

This study develops a 72k SNP array to assess BKD resistance in Arctic charr and finds genomic prediction is feasible with moderate accuracy.

Analysis of a hypomorphic mei-P26 mutation reveals coordination between developmental programming of germ cells and meiotic chromosome dynamics.

This study investigates how disrupting coordination between germ cell differentiation and meiosis in Drosophila affects meiotic chromosome dynamics using a hypomorphic mei-P26 mutation.

Full-length next-generation sequencing of 11 HLA loci of more than 1000 individuals from clinical cohorts in East and West Africa

The paper reports full-length NGS HLA genotyping of 1023 individuals from East and West Africa, identifying 371 unique alleles and 25 novel ones, including those with non-synonymous changes affecting peptide binding.

Overexpression of Eaf1, a subunit of the NuA4 lysine acetyltransferase complex, rescues growth defects in the budding yeast H3K36M oncohistone model via histone H4 tail acetylation

This paper shows that overexpressing Eaf1, a NuA4 subunit, rescues growth defects in yeast with H3K36M mutations by acetylating histone H4 tails.

Genomic Dimensionality Bounds Mixed-Model Association Power, Fine-Mapping Resolution, and Genomic Prediction Reliability

This paper develops a framework explaining differences in GWAS results between livestock and humans by linking them to effective genomic dimensionality and population genetics parameters.

Evaluating the potential role and contribution of transposable elements to the evolution of microbial multicellularity across the tree of eukaryotes

The paper examines the role of transposable elements in the evolution of multicellularity across protist lineages by analyzing TE composition, diversity, and gene regulation patterns.

Phloiokeratosis - a new ichthyosiform hyperkeratotic cornification disorder in dogs with SUV39H1 variants

This study identifies SUV39H1 variants in dogs with a new skin disorder, linking SUV39H1 deficiency to epidermal hyperkeratosis and highlighting its role in keratinocyte differentiation.

Reconciling the effects of PMS2 in different repeat expansion disease models supports a common expansion mechanism

The paper shows that PMS2 has similar effects in two different repeat expansion disease models, supporting a common expansion mechanism across Repeat Expansion Diseases.

Defining the molecular tolerance-to-damage landscape of SMARCA4 helicase genetic alterations

This study develops a helicase-specific variant effect predictor to classify SMARCA4 variants as damaging or tolerated, improving interpretation of genetic variants of uncertain significance.

Direct and indirect regulation of fetal globin transcript by RNA-binding protein IGF2BP1

This study identifies IGF2BP1 as a direct and indirect regulator of fetal globin transcripts through m6A modification and interaction with HIC2 and BCL11A.

Downregulation is the dominant effect of new regulatory mutations in a fungal pathogen

The paper analyzes genome sequencing data of Zymoseptoria tritici to show that new regulatory mutations predominantly cause gene downregulation.

Primary-Level Meta-Analysis of Diversity Outbred Mice Identifies a Fasting Plasma Trimethylamine N-Oxide (TMAO) Locus Modified by Sex and Diet

The paper identifies a TMAO locus on mouse chromosome 12 modified by sex and diet through a meta-analysis of 1,482 Diversity Outbred mice.

Classical HLA Allele and Haplotype Frequency Estimates in US Populations

The paper estimates HLA allele and haplotype frequencies in US populations using large-scale genotyping data, revealing population-specific diversity and shared haplotypes.

Is APOE ε2 always a protective allele? Deviations in Hardy-Weinberg equilibrium in admixed Brazilian elderly individuals

The paper examines APOE ε2's protective role in admixed Brazilian elderly populations, finding that local ancestry influences its effects on longevity and disease risk.

Mating strategies in Caenorhabditis elegans populations are determined by male developmental history

The paper shows that developmental history in Caenorhabditis elegans affects mating strategies, with postdauer males showing increased pheromone detection and outcrossing.

First genetic detection and ongoing eDNA monitoring of the golden mussel (Limnoperna fortunei) in California

The paper reports the first genetic confirmation of golden mussels in North America and develops eDNA monitoring procedures for early detection of invasive species.