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This study shows LTBP2 promotes TGF-beta signaling and lung fibrosis in mice but is also needed for epithelial repair.

This paper introduces a refined murine model of reversible aortic constriction to study cardiac functional recovery, finding that while function recovers, structural and fibrotic changes persist.

This study validates a high-throughput multiplex immunofluorescence method combined with computer-automated analysis for comprehensive immunophenotyping of Mycosis Fungoides.

This study shows that circadian clock genes BMAL1 and CLOCK regulate melanin synthesis in melanocytes by modulating vitamin D signaling.

This study investigates the biodistribution and effects of Ronapreve in a mouse model of SARS-CoV-2 infection, showing it does not reach the brain but reduces viral loads in the lung and brain.

The paper develops a deep learning tool to analyze endometrial histology and identifies morphological correlates of miscarriage risk.

This study shows that AngII infusion worsens aortic pathology in Fbn1C1041G/+ mice, leading to aortic rupture and branch aneurysms.

The paper investigates the association between Alzheimer's disease and Biondi body amyloid in hippocampal-associated choroid plexus epithelial cells and ependymal cells, finding a near-significant increase in BB-containing CPECs and a significant increase in BB-like amyloid in ependymal cells in AD.

This study identifies Rhizoctonia theobromae as the causal agent of cassava witches' broom disease in Brazil and suggests its recent introduction from Southeast Asia.

The paper identifies and characterizes Hexamita nelsoni in blue mussels, showing its presence in digestive glands and mantel, and suggests horizontal transmission from adult to larvae.

COLOR-3D improves 3D histology by enhancing dye penetration and enables quantitative analysis of tissue morphology and aging-related changes in mouse liver.

This study identifies age and adiposity-related lipid droplet accumulation in human choroid plexus epithelial cells, with associations with BMI, sex, and Alzheimer's Disease.

This study shows hepatocyte TEAD1 promotes fibrosis and inflammation in cholestatic liver injury but not bile acid metabolism, suggesting it as a therapeutic target in PSC.

This study generates two mouse models of nephronophthisis by inactivating Nphp3 at different developmental stages, revealing distinct disease mechanisms and treatment responses.

This study tracks the seasonal activity of Hyalomma marginatum ticks in southern France, showing their life cycle patterns and interactions with hosts and environmental factors.

This paper develops an interpretable AI framework for leukocyte morphology classification in peripheral blood smears, achieving high accuracy with reduced annotation needs and providing clinical tools for integration.

This paper develops a registration pipeline to align multimodal 3D imaging data from colon cancer tissue and uses unsupervised clustering to identify spatially coherent tissue regions.