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Analytic Hierarchy Process weights merge fold-change, FDR and protein-interaction centrality into a traceable composite ranking of 143 triple-negative breast cancer exosomal protein candidates.

FOCUS, a 100 µm atlas of 180 manually segmented subcortical grey and white matter regions and 77 hand-built tracts, registered to MNI 2009b space for warping to individual brains.

Targeted-learning GWAS of 1,268 UK Biobank ME/CFS cases found 176 FDR-significant variants; seven replicated in disjoint UK Biobank or All of Us cohorts.

In 30 six-month-olds, 2 Hz syllable sequences selectively raised delta EEG power in right frontal and left temporal clusters; right frontal tuning grew over blocks; voice familiarity altered theta responses.

Inferring tested-but-undetected pairs from prey lists of 5,530 published interaction screens yields 97 million tested human protein pairs and 18,982,508 non-interactions (≥3 tests) for calibrating screens and predictors.

Simultaneity-judgment training reduced flash-illusion susceptibility similarly in children with and without ADHD; Bayesian modelling showed lower common-cause prior in typical children versus lower temporal uncertainty in ADHD.

RIOK3 displaces eS26 from ubiquitinated 40S subunits, exposing the 18S rRNA 3' end for U-tailing by TUT4/TUT7 and exonucleolytic decay by DIS3L2, which commits defective subunits to turnover.

CTCF dimerization on stacked nucleosomes is resolved by cryo-EM through a ZnF6-7-8 interface. Disrupting it in mouse stem cells weakens CTCF-cohesin loops more than insulation and impairs germline differentiation.

Single-nucleus RNA+ATAC profiling of 32 mice shows asymmetric PRDM9 binding drives asynapsis, pachytene cell loss, aneuploidy and multi-megabase crossover redistribution, tuned by a chromosome 15 locus.

TIGRFinder annotated 6,685 TIGR arrays; cryo-EM structures show inactive RuvC domains, and E. coli reporter assays show CsTasR and MbTasA repress transcription in a guide-dependent manner.

Merging CellAge, GenAge, SenMayo and Reactome senescence genes onto Ensembl IDs yields 1,250 provenance-tracked genes, most also annotated with mouse/zebrafish orthologs, tissue expression and STRING interactions.

In 5-FU-treated mice, oral and intestinal epithelial atrophy stems from p53-linked cell cycle arrest, not apoptosis, while a chemoresistant AP-1/p53 basal cluster expands in tongue.

In larval zebrafish, 68% of 81 traced serotonergic dorsal raphe neurons target only one of telencephalon and spinal cord; stress in week 1, not week 2, raised telencephalic fiber density.

Leverage-weighted sketching plus sparse spatial regularization deconvolves 1.6 million Visium HD bins in 153 seconds on commodity hardware, revealing tissue-specific resolution limits where cell-type co-localization can reverse sign.

In ART-suppressed human brain, an SPP1+ activated microglial subset holds most detected HIV RNA and shows chronic interferon-I and MHC-I signatures, alongside complement signaling and neuronal loss.

Weekly leaf spectra and traits in seven temperate species reveal phenophase-dependent trait correlations; peak-season PLSR models fail at senescence while full-season models track trait dynamics.

A web database and REST API of 124,687 AlphaFold 3 structures for human splice isoforms, annotated against canonical proteins for domains, decay, modifications, neoantigens and drug pockets.

MycoAI ITS classifiers trail alignment, SINTAX and HiTaC on full-length ITS and drop to 28.3% and 18.5% seen-genus family accuracy on ITS2, as predictions track flanking regions.

40S subunit binding to a previously unrecognised RRM in LARP1 activates its TOP-binding HEAT repeats, licensing repression of ribosomal protein mRNA translation in human cells.

A conditional latent diffusion transformer predicts immunofluorescence images of 12,800 human proteins from nucleus, ER and microtubule stains, outperforming PUPS and CELL-Diff, including on an unseen drug-treated cell line.