A. Banerjee

This paper characterizes SaTTM, an archaeal CYTH protein, showing it functions as a triphosphatase rather than an adenylyl cyclase, with structural and biochemical insights into its mechanism.

This study uses active microrheology with optical tweezers to measure viscoelastic changes in lamin A mutants, linking structural alterations to disease mechanisms in laminopathies.

This study identifies pyruvate oxidase (SpxB) as critical for pneumococcal survival during transcytosis across the blood-brain barrier by enabling acid tolerance and lysosomal enzyme inactivation.

This study identifies Xist-seeded nucleation sites that create local concentration gradients of silencing proteins, leading to X-chromosome inactivation through macromolecular crowding.

This paper identifies structural changes in a non-hemolytic pneumolysin variant that disable pore formation, enabling pneumococcus to adopt an intracellular lifestyle with reduced inflammation and increased host tolerance.

This study shows SARS-CoV-2 and related coronaviruses induce processing body disassembly, with SARS-CoV-2's N protein uniquely causing this effect, leading to increased proinflammatory cytokine production.

This study examines the feeding preferences of free-ranging grey langurs in an urban setting, finding they prefer urban food items over natural ones due to resource scarcity and human interaction.

This paper introduces a Colon Intestine-Chip platform to study leaky gut by combining organoids and Organ-on-Chip technologies, showing its response to inflammatory cytokines and IL-22.

This study analyzes SARS-CoV-2 genomic diversity in India, identifying 33 mutations and classifying strains into 22 groups based on co-existing mutations.

This study shows SARS-CoV-2 infection induces a mild type I IFN response in vitro and in moderate COVID-19 cases, and cannot inhibit exogenous IFN induction.

This study examines how lamin A mutations alter the epigenetic landscape in C2C12 cells, identifying specific histone modifications and RNA polymerase II changes associated with dilated cardiomyopathy.

The paper isolates SARS-CoV-2 from two patients, sequences the virus, and tests its infectivity in human immune cells, finding that PBMCs are not permissive to infection.

The paper examines gene expression and protein localization of potential SARS-CoV-2 receptors in human airway epithelial cells and lung tissue, finding low ACE2 expression and confirming other candidate receptors.

The paper screens epitopes in SARS-CoV-2 spike glycoprotein using immuno-informatic methods to identify potential vaccine targets based on energetics, IC50, and antigenicity.

This study analyzes longitudinal genomic data from colorectal cancer patients to show that negative selection stabilizes karyotypes during tumor progression and metastasis.

This paper investigates how DHHC20 reshapes membranes to facilitate catalysis through biochemical and computational methods.

This study shows that vinculin loss in murine skin disrupts adherens junctions, leading to loss of bulge stem cell quiescence through impaired force generation and YAP1 retention.

This study uses carnivores in India to assess conservation priorities by integrating ecological, social, and economic factors, identifying gaps in current protected areas and suggesting alternative strategies.

The paper describes the UCSC Xena platform, which enables secure visualization and analysis of both public and private cancer genomics data through web-based tools and hubs.

The paper shows that succinate from commensal bacteria promotes tuft cell development and reduces ileal inflammation in a mouse model of Crohn's disease.

The paper identifies post-translational modifications (PTMs) on the Drosophila HOX protein Sex combs reduced (SCR) and evaluates their association with predicted short linear motifs (SLiMs).