Author

Jérôme Moreaux

Centre National de la Recherche ScientifiqueORCID 0000-0002-5717-3207Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A Reynaud· 1 shared Alain ChavanieuiD· 1 shared Alessandro Bani· 1 shared Alexis J. CombesiD· 1 shared Angelo PilottiiD· 1 shared Anne‐Marie MartineziD· 1 shared Antoine Aze· 1 shared Audrey Vernet· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A Reynaud

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A non-catalytic function for Rad18 in sustaining glioblastoma proliferation

Nour El Houda Benbahouche, Antoine Aze, Aurore Siegfried, Lenka Štefančíková, Chames Kermi, Jean‐Marc Pascussi, Julie Pannequin, Jérôme Moreaux, Tom Egger, Alain Chavanieu, Jean‐Philippe Hugnot, Marie‐Bernadette Delisle, Elizabeth Cohen‐Jonathan Moyal, Emmanuelle Uro‐Coste, Domenico Maiorano

This study identifies a non-catalytic role for Rad18 in sustaining glioblastoma proliferation and proposes it as a therapeutic target.

Cell Reports · Jul 1, 2026Peer-reviewedCancer Biology

Single-Nuclei Analysis of the Unfolded Protein Response (SNUPR): A Novel Method revealing bortezomib resistance mechanisms in Multiple Myeloma

Julien Paul Gigan, Paulina A García-González, Angelo Pilotti, Lou Galliot, A Reynaud, Yoan Ghaffar, Felipe Flores‐Santibáñez, Sara Ghafoori, Eve Seillier, Rosario Lavignolle, Daniela Barros, Caroline Bret, Sharon Fichaux, Alexis J. Combes, Alessandro Bani, , Rafael José Argüello

SNUPR enables single-cell UPR profiling and reveals the role of IRE-1 axis in predicting bortezomib resistance in multiple myeloma.

EMBO Molecular Medicine · Jun 29, 2026Peer-reviewedCancer Biology

Transient loss of Polycomb components induces an epigenetic cancer fate

Victoria Parreno, Vincent Loubière, Bernd Schuettengruber, Lauriane Fritsch, Chetan C. Rawal, Maksim Erokhin, Balázs Győrffy, Davide Normanno, Marco Di Stefano, Jérôme Moreaux, Nadejda L. Butova, Irene Chiolo, Darya Chetverina, Anne‐Marie Martinez, Giacomo Cavalli

The paper shows that transient loss of Polycomb components in Drosophila induces an irreversible cancer fate through epigenetic reprogramming without driver mutations.

Nature · Apr 24, 2024Peer-reviewedDevelopmental Biology

Regulation of oncogene-induced senescence by the MRE11 and TREX1 nucleases

Hervé Técher, Diyavarshini Gopaul, Jonathan Heuzé, Baptiste Leray, Audrey Vernet, Clément Mettling, Jérôme Moreaux, Yi‐Ching Lin, Philippe Pasero

This study shows that MRE11 promotes oncogene-induced senescence by slowing replication forks and activating the cGAS-STING pathway, while TREX1 prevents it by degrading cytosolic DNA.

bioRxiv · Mar 30, 2023 · PreprintMolecular Biology

Var I Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data

Mohammad Salma, Elina Alaterre, Jérôme Moreaux, Éric Soler

Var I Decrypt is a web-based tool for analyzing whole-exome sequencing data, enabling variant prioritization and functional analysis in clinical settings.

bioRxiv · Sep 2, 2022 · PreprintBioinformatics