Author

Esha Urs

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Alexander MarsoniD· 2 shared Julia C. CarnevaleiD· 2 shared Justin EyquemiD· 2 shared Peixin Amy CheniD· 2 shared Ana Vasquez-Ibarra· 1 shared Brian Rudolph ShyiD· 1 shared Carter ChingiD· 1 shared Chandrima Modak· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

Alexander MarsonORCID

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Author profile →

2 papers

Recent·Most cited

Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells

Hyuncheol Jung, Pascal Devant, Carter Ching, Mineto Ota, Emma Dann, Ronghui Zhu, Chandrima Modak, Ana Vasquez-Ibarra, Jennifer R. Hamilton, Zachary Steinhart, Wayne Ngo, Luis R Sandoval, Jae Hyung Jung, Jae Hyun J. Lee, Da Xu, , Julia C. Carnevale

This paper develops a virus-like particle-based system for CRISPR gene editing and screening in primary human myeloid cells, identifying TNFAIP3 as a key regulator of inflammatory polarization.

Nature Biotechnology · Aug 17, 2026Peer-reviewedImmunology

In vivo genome-wide CRISPR screens in human T cells to enhance T cell therapy for solid tumors

Qi Liu, Peixin Amy Chen, Esha Urs, Shimin Zhang, Maya M. Arce, Charlotte H. Wang, Zhongmei Li, Jin Seo, Nupura Kale, Taylor N. LaFlam, Fanglue Peng, Eric Shifrut, Greg M. Allen, Justin Eyquem, Katherine Cynthia Fuh, , Julia C. Carnevale

This paper performs in vivo CRISPR screens in human T cells to identify genetic modifiers of T cell function in solid tumors, finding P2RY8-G13 and GNAS as key regulators.

bioRxiv · Sep 23, 2025 · PreprintImmunology