Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
D. A. Bradburn, J. C. Reis, R. Y. Moreno, S. Qayyum, T. Viennet, H. Arthanari, M. S. Cyert
The paper identifies a novel composite motif in CLMB that enables multimeric dephosphorylation by calcineurin, influencing its membrane localization and signaling.
bioRxiv · May 12, 2024Biochemistry
B. H. Liu, M. Liu, S. Radhakrishnan, C. K. Jaladanki, C. Gao, J. Tang, K. Kumari, M. L. Go, K. A. Vu Le, H.-S. Seo, K. Song, X. Tian, F. Li, J. Tan, H. Arthanari, , C. Li
This study identifies a new IMiD-independent drug targeting SALL4's ZFC4 domain, leading to significant tumor growth inhibition in vivo.
bioRxiv · Jan 3, 2024Cancer Biology
Y.-S. Huoh, Q. Zhang, R. Torner, S. C. Baca, H. Arthanari, S. Hur
This paper identifies a multi-layered mechanism by which Aire forms transcriptional condensates on enhancers through coordinated interactions between its CARD, PHD1, and CTT domains.
bioRxiv · Oct 23, 2023Cell Biology
K. A. L. Vu, S. Moein, K. Kumari, B. H. Liu, C. Gao, M. Liu, M.-Y. Dai, Z. Liu, F. Li, J. P. Tang, D. Maddalo, D. S. Auld, D. E. Casalena, X. Tian, M. A. Bassal, , L. Chai
The paper identifies a compound that degrades both SALL4 isoforms, overcoming IMiD limitations in liver cancer treatment.
bioRxiv · Jul 7, 2023 · PreprintCancer Biology
J.-C. Twizere, S. Maseko, Y. Brammerloo, I. Van.Molle, A. Sogues Castrejon, C. Martin, C. Gorgulla, J. Olivet, J. Blavier, T. Ntombela, D. Frank, H. Arthanari, H. Remaut, K. Salehi-Ashtiani, S. Ballet, O. Volkov
The paper identifies a small molecule that inhibits the Tax-1-hDLG1 interaction, reducing HTLV-1 cell-to-cell transmission in a T-cell model.
bioRxiv · Mar 15, 2023Biochemistry
B. Meszaros, A. Hatos, N. Palopoli, F. Quaglia, E. Salladini, K. Van Roey, H. Arthanari, Z. Dosztanyi, I. C. Felli, P. D. Fischer, J. Hoch, C. M. Jeffries, S. Longhi, E. Maiani, S. Orchard, , N. E. Davey
The paper introduces MIADE guidelines to standardize metadata for experiments studying intrinsically disordered proteins, improving data interpretation and reproducibility.
bioRxiv · Jul 12, 2022 · PreprintScientific Communication & Education
H. Bae, T. Viennet, E. Park, N. Chu, A. Salguero, M. J. Eck, H. Arthanari, P. A. Cole
This study identifies a mutation in the PH domain of Akt that enhances autoinhibition and reveals the molecular mechanism of Akt activation as an oncogenic driver.
bioRxiv · May 25, 2022Biochemistry
S. Maseko, I. Van Molle, K. Blibek, C. Gorgulla, J. Olivet, J. Blavier, C. Vandermeulen, S. Skupiewski, D. Saha, T. Ntombela, J. Lim, F. Lembo, A. Beauvois, M. Hamaidia, J.-P. Borg, , J.-C. Twizere
This study identifies the structural basis of Tax-1 interaction with syntenin-1 and demonstrates small-molecule inhibition of this interaction to target HTLV-1.
bioRxiv · Aug 25, 2021 · PreprintBiochemistry
V. S. De Paula, A. Dubey, H. Arthanari, N. Sgourakis
This study identifies a conformational switch in Cas9 that reduces off-target cleavage by enabling REC3 domain scanning for proper base pairing.
bioRxiv · Dec 6, 2020 · PreprintBiochemistry
G. G. Rossetti, M. Ossorio, S. Barriot, L. Tropia, V. S. Dionellis, C. Gorgulla, H. Arthanari, P. Mohr, R. Gamboni, T. D. Halazonetis
The paper identifies low micromolar SARS-CoV-2 Mpro inhibitors from in silico screens through biochemical testing of synthesized compounds.
bioRxiv · Dec 3, 2020 · PreprintBiochemistry