Author

Jennifer Shih

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1

Frequent Co-Authors

Mriganka SuriD· 4 shared Chloe DelepineiD· 2 shared Keji LiiD· 2 shared Kyle R. JenksiD· 2 shared Aaron N. Chang· 1 shared Amy K.Y. FuiD· 1 shared Andrew S. KhaliliD· 1 shared Angela M. CacaceiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersNeuroscience

Mriganka SurORCID

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4 papers

Recent·Most cited

The noncoding circular RNA circHomer1 regulates synaptic development and experience-dependent plasticity in mouse visual cortex

Kyle R. Jenks, Ying Cai, Marvin Eduarte Nayan, Katya Tsimring, Keji Li, José C. Zepeda, Greggory R. Heller, Chloe Delepine, Jennifer Shih, Shiyang Yuan, Yao Zhu, Ye Wang, Yangyang Duan, Amy K.Y. Fu, Taeyun Ku, , Jacque Pak Kan Ip

This study identifies circHomer1 as a circRNA critical for synaptic development and experience-dependent plasticity in mouse visual cortex through transcriptome analysis and knockdown experiments.

iScience · Aug 22, 2025Peer-reviewedNeuroscience

Cortical astrocytes extend phasic norepinephrine signals and critically mediate learned behavior

Gabrielle T Drummond, Arundhati Natesan, Marco Celotto, Jiho Park, Jennifer Shih, Prachi Ojha, Yuma Osako, Giselle Fernandes, Kyle R. Jenks, Grayson O. Sipe, Vincent Breton‐Provencher, Tatsuya Osaki, Paul C. Simpson, Stefano Panzeri, Mriganka Sur

The paper shows that cortical astrocytes mediate learned behavior by extending norepinephrine signals through calcium dynamics and ATP release, influencing neuronal encoding of task variables.

bioRxiv · Oct 24, 2024 · PreprintNeuroscience

Fragile X syndrome patient-derived neurons developing in the mouse brain show FMR1 -dependent phenotypes

Marine Krzisch, Hao Wu, Bingbing Yuan, Troy W. Whitfield, X. Shawn Liu, Dongdong Fu, Carrie M. Garrett-Engele, Andrew S. Khalil, Tenzin Lungjangwa, Jennifer Shih, Aaron N. Chang, Stephen T. Warren, Angela M. Cacace, Kristin R. Andrykovich, Rosalie G. J. Rietjens, , Rudolf Jaenisch

This study transplants FXS patient-derived neurons into mice to study their development and finds FMR1-dependent changes in synaptic activity and morphology.

Biological Psychiatry · Jan 1, 2023Peer-reviewedNeuroscience

Astrocyte glutamate transport is modulated by motor learning and regulates neuronal correlations and movement encoding by motor cortex neurons

Chloe Delepine, Keji Li, Jennifer Shih, Pierre Gaudeaux, Mriganka Sur

bioRxiv · Jan 20, 2022 · PreprintNeuroscience