Kiet Ngo

Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits

The paper presents an enhancer AAV toolbox for targeting and perturbing striatal cell types and circuits in mice, with validated specificity and cross-species applicability.

A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types

The paper develops a toolkit of transgenic mouse lines and enhancer AAVs for selective targeting of cortical cell populations using transcriptomic and epigenomic data.

Local Connectivity and Synaptic Dynamics in Mouse and Human Neocortex

The paper presents a synaptic physiology dataset and analysis platform to study cortical microcircuit structure and synaptic properties in mouse and human neocortex, revealing layer-dependent connectivity and subclass-specific dynamics.

Reconciling functional differences in populations of neurons recorded with two-photon imaging and electrophysiology

This study compares neuronal responses in visual cortex using electrophysiology and two-photon imaging in awake mice, finding differences in responsiveness and selectivity and exploring data transformations to reconcile them.

A survey of spiking activity reveals a functional hierarchy of mouse corticothalamic visual areas

The paper presents a dataset and analysis of spiking activity across multiple mouse visual areas, revealing that functional connectivity mirrors anatomical hierarchy.

Toward an integrated classification of neuronal cell types: morphoelectric and transcriptomic characterization of individual GABAergic cortical neurons

The paper characterizes transcriptomic and physiological properties of GABAergic cortical neurons in mice, identifying 20 interneuron met-types with consistent features across modalities.

Distinct transcriptomic cell types and neural circuits of the subiculum and prosubiculum along the dorsal-ventral axis

The paper identifies 27 transcriptomic cell types in mouse subiculum and prosubiculum, defines their anatomical boundaries, and reveals distinct neural circuits and projections along the dorsal-ventral axis.

Human cortical expansion involves diversification and specialization of supragranular intratelencephalic-projecting neurons

The paper identifies transcriptomic diversity in human supragranular neurons and links it to functional specialization and disease vulnerability.

Classification of electrophysiological and morphological types in mouse visual cortex

The paper classifies neurons in mouse visual cortex into 17 electrophysiological and 35 morphological types using unsupervised methods and links them to transcriptomic types.