Author

Loan Tran

Ludwig Boltzmann Institute Applied Diagnostics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Carlos Uziel Pérez MallaiD· 2 shared Gerda EggeriD· 2 shared Jessica KallaiD· 2 shared Raheleh Sheibani‐TezerjiiD· 2 shared Aislinn Gonnot· 1 shared Andreas TiefenbacheriD· 1 shared Anil Baskan· 1 shared Anna MalzeriD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Carlos Uziel Pérez MallaORCID

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3 papers

Recent·Most cited

Aggressive KRAS mutations direct TGF-β response towards partial EMT in patient-derived colorectal cancer tumoroids

Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, , Gerda Egger

This study investigates how TGF-β affects colorectal cancer tumoroids, finding that aggressive KRAS mutations lead to partial EMT and increased invasiveness.

Molecular Oncology · Mar 11, 2025Peer-reviewedCancer Biology

Identification of Biomarkers and Trajectories of Prostate Cancer Progression: A Bioinformatics Fusion of Weighted Correlation Network Analysis and Machine Learning

Raheleh Sheibani‐Tezerji, Carlos Uziel Pérez Malla, Gabriel Wasinger, Katarina Mišura, Astrid Haase, Anna Malzer, Jessica Kalla, Loan Tran, Gerda Egger

This study identifies biomarkers and trajectories of prostate cancer progression using bioinformatics fusion of weighted correlation network analysis and machine learning, finding the EZH2-TROAP axis as a key trajectory and 58 validated biomarkers.

bioRxiv · Mar 2, 2023 · PreprintBioinformatics

Cell-free prototyping enables implementation of optimized reverse beta-oxidation pathways in heterotrophic and autotrophic bacteria

Bastian Vögeli, Luca Schulz, Shivani Garg, Katia Tarasava, James M. Clomburg, Seung Hwan Lee, Aislinn Gonnot, Elamar Hakim Moully, Blaise R. Kimmel, Loan Tran, Hunter Zeleznik, Steven D. Brown, Séan Dennis Simpson, Milan Mrksich, Ashty S. Karim, , Michael C. Jewett

The paper optimizes and implements reverse beta-oxidation pathways in bacteria for carbon-negative synthesis of C4-C6 acids and alcohols, achieving high product titers in engineered strains.

Nature Communications · Jun 1, 2022Peer-reviewedSynthetic Biology