Author

Milan Mrksich

Northwestern UniversityORCID 0000-0002-4964-796XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Organism:human· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Assay:protein sequence· 1

Frequent Co-Authors

Lin LiangiD· 2 shared Michael C. JewettiD· 2 shared Aislinn Gonnot· 1 shared Allen Yang· 1 shared Anthony J. AgbayiD· 1 shared Aravind NatarajaniD· 1 shared Ariel Helms ThamesiD· 1 shared Ashty S. KarimiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersSynthetic Biology

Lin LiangORCID

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Author profile →

3 papers

Recent·Most cited

Cell-free prototyping enables implementation of optimized reverse beta-oxidation pathways in heterotrophic and autotrophic bacteria

Bastian Vögeli, Luca Schulz, Shivani Garg, Katia Tarasava, James M. Clomburg, Seung Hwan Lee, Aislinn Gonnot, Elamar Hakim Moully, Blaise R. Kimmel, Loan Tran, Hunter Zeleznik, Steven D. Brown, Séan Dennis Simpson, Milan Mrksich, Ashty S. Karim, , Michael C. Jewett

The paper optimizes and implements reverse beta-oxidation pathways in bacteria for carbon-negative synthesis of C4-C6 acids and alcohols, achieving high product titers in engineered strains.

Nature Communications · Jun 1, 2022Peer-reviewedSynthetic Biology

Chemical precision glyco-mutagenesis by glycosyltransferase engineering in living cells

Benjamin Schumann, Stacy Alyse Malaker, Simon Wisnovsky, Marjoke F. Debets, Anthony J. Agbay, Daniel Fernández, Lauren J. S. Wagner, Lin Liang, Zhen Li, Junwon Choi, Douglas Fox, Jessie Peh, Melissa Anne Gray, Kayvon Pedram, Jennifer J. Kohler, , Carolyn Ruth Bertozzi

The paper introduces a method to chemically tag glycans in living cells using engineered glycosyltransferases to study glycan structure and biosynthesis.

Molecular Cell · Apr 22, 2020Peer-reviewedSynthetic Biology

A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

Weston Kightlinger, Katherine E. Duncker, Ashvita Ramesh, Ariel Helms Thames, Aravind Natarajan, Jessica C. Stark, Allen Yang, Lin Liang, Milan Mrksich, Matthew P. DeLisa, Michael C. Jewett

The paper introduces a cell-free platform for assembling protein glycosylation pathways and demonstrates its use in creating vaccine proteins and antibody constant regions with specific glycan motifs.

Nature Communications · Nov 27, 2019Peer-reviewedSynthetic Biology