M. Sharma

TOR coordinates with transcriptional and chromatin machinery to regulate thermotolerance and thermomemory

This study identifies Glc-TOR signaling's role in regulating thermotolerance and thermomemory in plants through transcriptional and epigenetic mechanisms.

Does visitation dictate animal welfare in captivity? A case study of tigers and leopards from National Zoological Park, New Delhi

This study examines the impact of visitor density on stereotypic behaviors in tigers and leopards at a zoo, finding significant associations with visitor numbers but not ambient noise.

Rhes, a Striatal Enriched Protein, Regulates Post-Translational Small-Ubiquitin-like-Modifier (SUMO) Modification of Nuclear Proteins and Alters Gene Expression

This study identifies Rhes as a regulator of SUMOylation of nuclear proteins and shows its role in modulating striatal gene expression through SUMO-dependent mechanisms.

In silico analysis of SNPs in human phosphofructokinase, Muscle (PFKM) gene: An apparent therapeutic target of aerobic glycolysis and cancer

The paper computationally identifies functional SNPs in the PFKM gene and associates them with cancer, highlighting potential therapeutic targets.

Root specific plasticity induced by paclobutrazol confers improved deficit irrigation tolerance and agronomic performance in maize

This study shows that paclobutrazol improves drought tolerance and agronomic performance in maize by enhancing root developmental traits under deficit irrigation.

Dual targeting of TatA points to a chloroplast-like Tat pathway in plant mitochondria

The paper demonstrates that TatA can be imported into both chloroplasts and mitochondria, suggesting a shared Tat transport mechanism in plant endosymbiotic organelles.

A sulfoglycolytic Entner-Doudoroff pathway in Rhizobium leguminosarum bv. trifolii SRDI565

This paper identifies a sulfoglycolytic Entner-Doudoroff pathway in Rhizobium leguminosarum that allows growth on sulfoquinovose, producing sulfolactate and contributing to bacterial persistence in soil.

Trait evolution under multiple selection pressures: Prey responses to predictable and unpredictable variation

The paper examines how prey behavior is shaped by predictable and unpredictable predation risks and other selection pressures, finding that females balance multiple risks when choosing oviposition sites.

Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment

This study shows that β-adrenergic receptor signaling regulates cardiomyocyte cytokinesis, and β-blockers like propranolol can enhance division in ToF/PS cardiomyocytes, potentially improving heart function in CHD patients.

Sustained exposure to trypsin causes cells to transition into a state of reversible stemness that is amenable to transdifferentiation

This paper shows that sustained trypsin exposure induces cells to transition into a reversible stem-like state, enabling transdifferentiation and altering cellular behavior.

Menace to the ultimate antimicrobials among common Enterobacteriaceae clinical isolates in part of North-East India

The study assesses carbapenem resistance in Enterobacteriaceae clinical isolates from upper Assam, finding 18.9% resistance and high multi-drug resistance.

Determining targeting specificity of nuclear-encoded organelle proteins with the self-assembling split fluorescent protein toolkit

The paper improves the sasplit-FP method to detect protein targeting specificity and develops a toolkit for high-throughput analysis of plastid and mitochondrial targeting in plants.

Sexual selection drives the evolution of wing interference patterns.

This study shows that wing interference patterns in Drosophila simulans evolve under sexual selection and correlate with male attractiveness.

Structural insights into unique features of the human mitochondrial ribosome recycling

The paper presents a cryo-EM structure of the human mitoribosome-RRFmt complex, revealing unique structural features and interactions involved in mitoribosome recycling.

Assignment of the resting state of the secondary active transporter BetP by integrating spectroscopic measurements and molecular simulations

The paper assigns the resting state of BetP by integrating spectroscopic measurements and molecular simulations to clarify its transport mechanism.