Q. Tang

This study shows that ADAR1's Z domain prevents IFN responses by recognizing Z-RNA, and its absence leads to spontaneous IFN induction and improved viral control.

This study shows that DNA ligase I fidelity affects the mutagenic ligation of pol β insertion products and repair intermediates with mismatches, and how APTX and FEN1 remove 5-AMP blocks.

This paper shows that CD28-TMD in CARs forms heterodimers with endogenous CD28, affecting T-cell responses and surface expression.

This study shows TIN2 promotes TRF1-mediated DNA-DNA bridging on telomeres, stabilizing interactions that depend on telomere length and sequence.

This paper develops dual orthosteric-allosteric inhibitors of PfHT1 that selectively target malaria parasites over human cells, showing potent activity against multidrug-resistant strains.

This study characterizes the subcellular localization of SARS-CoV-2 proteins using expression in human cells and immunofluorescent assays, revealing their association with various organelles.

This study investigates L-arabinose's antifeedant effects on cotton bollworm caterpillars, showing it deters feeding, suppresses gustatory responses, and inhibits sucrase activity.

The paper identifies biochemically neutral positions in human liver pyruvate kinase by analyzing evolutionary patterns and functional outcomes of amino acid substitutions.

Click-ExM expands super-resolution imaging to all biomolecules by integrating click-labeling into expansion microscopy.

The paper shows that cell-substrate adhesion drives Scar/WAVE phosphorylation, which limits pseudopod lifetime, independent of chemotactic signals.

The paper identifies point mutations that mimic allosteric effectors in human liver pyruvate kinase to validate potential drug targets for treating diabetes.

This study demonstrates that FAdV-4 penton-dodecahedron (Pt-Dd) and recombinant fiber-1 proteins induce strong immune responses and 100% protection against FAdV-4 in chickens, making them viable vaccine candidates.

The paper presents the structure of human TRPC6 ion channel in complex with inhibitor BTDM, revealing its architecture and inhibition mechanism.