R. Gupta

The paper documents freshwater ciliate diversity in Delhi, India, identifying 55 species across multiple classes and finding highest diversity at Okhla bird sanctuary.

The paper reveals metabolic plasticity in cancer through isomer-resolved lipidomics, identifying apocryphal pathways for lipid desaturation and their impact on lipid structure and function.

This study models IKZF1 lesions in B-ALL to show distinct chemosensitivity patterns and therapeutic vulnerabilities, identifying cytarabine sensitivity and JAK/STAT upregulation as potential targets.

The paper introduces DisCo, a deterministic scRNA-seq method for small tissue samples, revealing new intestinal organoid subtypes and stem cell populations.

The paper identifies a methionine-induced mechanism where Ppm1-mediated PP2A methylation stabilizes Gcn4, enabling anabolic growth programs.

This study shows that the SecA motor generates mechanical force to unfold substrate proteins during translocation, enabling efficient protein export.

This study shows cytokinin induces immunity and fungal pathogen resistance in tomato by modulating PRR trafficking, dependent on SA and ET.

This study shows that nitrogen-dependent yield response in Setaria italica is driven by grain number and genotypes, with low N responsive genotypes showing greater transcriptional changes under varying nitrogen levels post-flowering.

This study identifies therapy-induced lipid uptake and remodeling as drivers of ferroptosis hypersensitivity in prostate cancer, offering new strategies to combat drug resistance.

The paper validates the use of CAL2 antibody for detecting CALR mutations in MPNs through immunohistochemistry and confirms its specificity to mutated CALR in ET and MDS/MPN.

This paper investigates how MCM2-7 complexes are maintained across cell divisions to ensure genome stability, finding that MCMBP facilitates the nuclear import of nascent MCM3-7 subunits to sustain pre-RC formation.

The paper identifies a family of non-coding RNAs in actinobacteria that regulate metabolic state by recruiting ANTAR proteins to target transcripts, promoting reductive metabolism in mycobacteria.

The paper investigates the origin of HIV in the CNS of ART-suppressed individuals and finds T cell-derived HIV that can lead to drug resistance.