R. Zhang

This study shows HCC-1 promotes atherosclerosis by inducing pyroptosis in endothelial cells and macrophages and suggests it as an early diagnostic biomarker.

The paper develops a stochastic model of colonic crypt cell dynamics to quantify homeostasis and predict early tumorigenesis by analyzing the effects of APC and KRAS mutations.

This study demonstrates that MinION-only sequencing can accurately assemble giant virus genomes, enabling rapid genome-wide analysis of newly isolated viruses.

This study identifies Cdc14's role in regulating Rim4-mRNA complex assembly and stability during meiosis through phosphorylation and spatial dynamics.

The paper shows autophagy selectively degrades Rim4 during meiosis, sparing bound mRNAs for programmed translation.

The paper analyzes NRE sequences in RLKs and RLCKs from 528 plants to uncover structural-functional relationships and phosphorylation motifs, revealing their role in kinase regulation.

This study shows that stromal compartments in a mouse model of BPH are resistant to castration-induced regression, suggesting the need for additional therapies.

This study shows that moderate high temperature (35°C) benefits Chlamydomonas reinhardtii growth with acetate but harms it without, highlighting carbon metabolism's role in thermotolerance.

The paper isolates and characterizes a novel lytic vibriophage, R16F, which shows potential as a biocontrol agent against V. parahaemolyticus due to its specificity and lack of virulence factors.

This study shows O-GlcNAcylation of YTHDF1 enhances its cytosolic localization and promotes colorectal cancer by increasing c-Myc expression.

This study evaluates hydrogen sulfide (H2S) as a cytoprotective agent to enhance mesenchymal stem cell survival under cytotoxic calcium and phosphate conditions, showing that a novel H2S donor, GluSH, supports cell proliferation and osteoblast differentiation.

This study develops bifunctional CAR-NK cells targeting CD33 with anti-CD16 antibody secretion, showing improved antitumor effects against AML in vitro and in vivo.

The paper measures the bending stiffness of the bacterial flagellar hook under counterclockwise and clockwise rotations, finding it doubles under clockwise rotation.

This study shows that B. velezensis SQR9 alters rhizosphere microbial community structure and promotes cooperation among Bacillus species, enhancing plant growth.

This paper quantifies causality from head motion to eye movement using transfer entropy to assess driving performance in virtual reality.

The paper identifies and characterizes unannotated proteins in green lineage species, finding many with novel structures and potential plastid functions.

The paper shows HY5 regulates GLK transcription factors to control chloroplast development and hypocotyl elongation during light-induced seedling development in Arabidopsis.

This study shows that mesenchymal stem cells (MSCs) reduce CAR-T cell effectiveness against lymphoma by altering the microenvironment via stanniocalcin-1.

The paper identifies silk-like proteins as the main components of nacre matrix proteins, showing over 90% composition in both soluble and insoluble fractions.

This paper identifies a 4-bp deletion in the maize ZmSOS1 gene that causes salt sensitivity and develops a molecular marker to improve salt tolerance in breeding programs.

This study develops a potent non-covalent inhibitor of SARS-CoV-2 3CLpro, showing effective antiviral activity in human cells and animal models.

This study shows that eCIS in Streptomyces coelicolor mediate developmentally regulated intra-strain cell death, not defense against other species.

This study presents a DIA-based workflow to analyze PTMs in mouse brains, identifying SIRT5-regulated malonylation and succinylation sites and their impact on metabolic and neurodegenerative pathways.

This paper develops equine polyclonal antibodies that broadly neutralize major SARS-CoV-2 variants, showing high efficacy in vitro and ex vivo with low cost and potential for large-scale production.

This study identifies 933 heat tolerance genes in Chlamydomonas reinhardtii through genome-wide mutant screens, showing 50% have orthologs in crops and Arabidopsis mutants are heat sensitive.

This paper predicts SARS-CoV-2 antigenic evolution using MLAEP, a deep learning model that identifies mutations associated with immune escape and validates them through experiments.

The paper analyzes a branching process model of colorectal cancer initiation to estimate waiting times for novel driver mutations.

An intranasal SARS-CoV-2 beta variant subunit booster vaccine induced protective immunity against beta variant infection in rhesus macaques one year after initial vaccination.