Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
S. E. Bergholtz, Y. Jing, R. A. Kulkarni, T. T. Zengeya, J. L. Meier
This study synthesizes and evaluates a stable isostere of malonyllysine, demonstrating its resistance to decarboxylation and antibody recognition.
bioRxiv · Aug 23, 2020 · PreprintBiochemistry
M. Perez, D. W. Bak, S. E. Bergholtz, D. R. Crooks, Y. Yang, W. M. Linehan, E. Weerapana, J. L. Meier
The paper reports a chemoproteomic analysis of cysteine reactivity in HLRCC cells upon FH rescue, revealing transcriptional and posttranslational regulation of cysteine residues.
bioRxiv · Jun 25, 2020Cancer Biology
S. E. Bergholtz, C. A. Briney, S. S. Najera, M. Perez, M. Linehan, J. L. Meier
This study develops chemical agonists to induce S-succination, a posttranslational modification linked to oncometabolites, and demonstrates their cellular effects.
bioRxiv · Jan 11, 2020Biochemistry
M. J. Levy, D. C. Montgomery, M. E. Sardiu, S. E. Bergholtz, K. D. Nance, J. Montano, A. L. Thorpe, S. D. Fox, Q. Lin, T. Andresson, L. Florens, M. P. Washburn, J. L. Meier
The paper develops a chemoproteomic platform to analyze acyl-CoA/protein interactions and identifies biological processes affected by acetyl-CoA levels.
bioRxiv · Jul 18, 2019Biochemistry
R. A. Kulkarni, D. W. Bak, D. Wei, S. E. Bergholtz, C. A. Briney, J. H. Shrimp, A. L. Thorpe, A. Bavari, A. Alpsoy, M. Levy, L. Florens, M. P. Washburn, E. C. Dykhuizen, N. Frizzell, E. Weerapana, , J. L. Meier
This study maps fumarate's covalent targets using chemoproteomic probes and identifies cysteine residues affected by fumarate or FH mutations in HLRCC cells.
bioRxiv · Mar 22, 2018Cancer Biology