Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
R. C. Zimmermann, M. E. Sardiu, C. A. Manton, M. S. Miah, C. A. Banks, M. K. Adams, D. C. Koestler, D. R. Hurst, M. D. Edmonds, M. P. Washburn, D. R. Welch
This study identifies BRMS1 interactions and phosphorylation events that influence cell migration and metastasis in breast cancer.
bioRxiv · Feb 4, 2021 · PreprintCancer Biology
S. Oh, J. Lee, S. K. Swanson, L. Florens, M. P. Washburn, J. L. Workman
The paper identifies Tda1 as the kinase responsible for H3pT11 phosphorylation under low glucose stress, showing its regulation by AMPK and CK2 signaling in yeast.
bioRxiv · Nov 3, 2020Cell Biology
J. Lee, S. Oh, S. Bhattacharya, Y. Zhang, L. Florens, M. P. Washburn, J. L. Workman
This study shows that the pyruvate dehydrogenase complex (PDC) is salt-labile and structurally variable, with activity affected by ionic strength.
bioRxiv · Jun 2, 2020Biochemistry
W. C. Hahn, J. W. Kim, C. Berrios, M. Kim, A. E. Schade, G. Adelmant, H. Yeerna, E. Damato, A. B. Iniguez, S. K. Swanson, L. Florens, M. P. Washburn, K. Stegmaier, N. S. Gray, P. Tamayo, , J. DeCaprio
The paper shows STRIPAK directs PP2A to dephosphorylate MAP4K4, promoting oncogenic transformation via YAP1 activation.
bioRxiv · Oct 29, 2019Cancer Biology
M. J. Levy, D. C. Montgomery, M. E. Sardiu, S. E. Bergholtz, K. D. Nance, J. Montano, A. L. Thorpe, S. D. Fox, Q. Lin, T. Andresson, L. Florens, M. P. Washburn, J. L. Meier
The paper develops a chemoproteomic platform to analyze acyl-CoA/protein interactions and identifies biological processes affected by acetyl-CoA levels.
bioRxiv · Jul 18, 2019Biochemistry
V. Cloud, A. Thapa, P. Morales-Sosa, T. Miller, E. Momtahan, J. L. Jack, P. Gerhart, E. Leiva, S. R. Rapp, S. A. Miller, D. Holsapple, L. G. Shelton, R. A. Pierce, S. Martin-Brown, L. Florens, , R. D. Mohan
bioRxiv · Jun 25, 2019Cell Biology
S. Miah, C. Banks, Y. Ogunbolude, E. Bagu, J. MacAusland-Berg, A. Saraf, G. Hattem, C. Kempf, M. Sardiu, S. Napper, L. Florens, K. E. Lukong, M. P. Washburn
This study shows BRK phosphorylates SMAD4, leading to its proteasomal degradation and inhibition of the tumor suppressor FRK, which promotes metastasis.
bioRxiv · Dec 7, 2018Cancer Biology
M. Pagano, Y.-T. Jeong, D. Simoneschi, S. Keegan, D. Melville, N. Adler, A. Saraf, L. Florens, M. P. Washburn, C. Cavasotto, D. Fenyö, A. M. Cuervo, M. Rossi
This study identifies the ULK1-FBXW5-SEC23B pathway as a regulator of autophagy by controlling COPII localization and SEC23B stability during nutrient starvation.
bioRxiv · Oct 12, 2018Cell Biology
N. Zhou, A. Gutierrez Uzquiza, X. Y. Zheng, D. Vogl, A. L. Garfall, L. Bernabei, A. Saraf, L. Florens, M. P. Washburn, A. Illendula, J. H. Bushweller, L. Busino
This study identifies RUNX1 and RUNX3 as proteins that protect IKZF1 and IKZF3 from lenalidomide-induced degradation, thereby reducing the effectiveness of lenalidomide in multiple myeloma.
bioRxiv · Sep 20, 2018Cancer Biology
R. A. Kulkarni, D. W. Bak, D. Wei, S. E. Bergholtz, C. A. Briney, J. H. Shrimp, A. L. Thorpe, A. Bavari, A. Alpsoy, M. Levy, L. Florens, M. P. Washburn, E. C. Dykhuizen, N. Frizzell, E. Weerapana, , J. L. Meier
This study maps fumarate's covalent targets using chemoproteomic probes and identifies cysteine residues affected by fumarate or FH mutations in HLRCC cells.
bioRxiv · Mar 22, 2018Cancer Biology
W. B. Redwine, M. E. DeSantis, I. Hollyer, Z. M. Htet, P. T. Tran, S. K. Swanson, L. Florens, M. P. Washburn, S. L. Reck-Peterson
The paper identifies ninein and ninein-like as new dynein activators using BioID, revealing their role in cargo binding and motility.
bioRxiv · May 30, 2017Cell Biology