S. Wang

This paper develops a lipid-specific quantum dot labeling method to track enveloped viruses, showing it preserves virus integrity and enables efficient tracking of viral infection dynamics.

The paper uses single-cell RNA-seq data to identify subclonal compositions in TNBC and links them to survival outcomes and immune microenvironment diversity.

The paper develops a method to measure multiscale chromatin folding and nuclear structures in single cells, revealing cell-type-specific architectures and physical principles of chromatin organization.

This study shows that cleavage of a pathogen protein by plant proteases activates immunity, while pathogens counteract this with inhibitors.

The paper shows that boron deficiency reduces brassinolide accumulation by downregulating BR6ox1 and BR6ox2, thereby inhibiting root growth through BR signaling.

This study identifies RpvA, a LysR-type regulator in S. aureus, which controls persister formation and virulence by modulating metabolism and virulence gene expression.

The paper identifies a pleiotropic gene block associated with plumage coloration that drives early differentiation between two hybridizing warbler species.

The paper introduces GLAMS, a method using glycosyltransferase labeling and mass spectrometry to identify sialylation linkages at the glycopeptide level, successfully identifying 1,236 linkage-specific sialoglycopeptides from human serum.

This study establishes a trans-resveratrol-induced mouse pulmonary fibrosis model and compares it to the bleomycin-induced model, finding it causes less damage and progresses more slowly.

This study develops a serum-free method to generate human mesenchymal stem cell spheroids using knockout serum replacement, showing similar transcriptomes to FBS-based spheroids and retained MSC markers.

This paper improves pulcherriminic acid production in Bacillus licheniformis through multistep metabolic engineering, achieving a record yield of 556.1 mg/L.

This paper investigates the hydrodynamics of flying fish taxiing on water surfaces before take-off, finding that taxiing requires significantly less power than swimming and allows for higher speeds.

This paper describes an inquiry-based laboratory module for synthetic biology where students design DNA sequences to maximize GFP expression using DNA assembly techniques.

The paper introduces a timescale-specific variance ratio metric to quantify compensatory dynamics in ecological communities and applies it to grassland data, showing variation in compensation across timescales.

This meta-analysis evaluates the prognostic value of Red Blood Cell Distribution Width (RDW) in Acute Kidney Injury (AKI) patients, finding a significant association but noting limitations due to small sample sizes.

The paper crosses Pholiota adiposa and P. limonella to develop a high-yield hybrid strain for commercial cultivation.

PIRD is a database that collects and stores annotated TCR and BCR sequencing data, along with tools for visualization and analysis.

This study uses smFRET to show circovirus capsid undergoes reversible conformational changes, regulated by heparan sulfate and neutralizing antibodies, revealing dynamics in receptor binding.

This study shows that adding extracellular polymer substances (EPS) increases methane production in anaerobic digestion by enhancing microbial communities and electron transfer, without affecting sludge properties.

The paper performs single-cell RNA sequencing on TNBC tumors to identify novel immune cell subsets and their associations with survival and TCR signaling.

This study identifies stable reference genes for RT-qPCR normalization in Hypericum perforatum across tissues, developmental stages, and stress conditions.

This study identifies multiple noncanonical PAMs recognized by SpCas9 in human cells, improving understanding of off-target mutation risks.

IL-2 mutein treatment expands multiple sub-states of Tregs with superior suppressive function in mice.

This study quantifies selective pressures on human pigmentation genes across populations and time periods, finding directional selection on light and dark pigmentation traits.

This study introduces a method using a single FT expression cassette in CRISPR/Cas9 to rapidly generate and identify transgene-free mutants in Arabidopsis.

The paper develops novel inhibitors targeting DHFR enzymes in MRSA to overcome trimethoprim resistance, showing low nanomolar activity and human selectivity.

This study demonstrates that full-length human tau can be displayed on yeast surface, enabling analysis of its conformational changes and interactions without phosphorylation observed in Alzheimer's disease.

The paper develops a high-content Virion Display (VirD) array of human GPCRs to profile their biochemical activities and identifies potential drug targets.

The paper reveals a new mechanism by which basement membrane regulates fibronectin organization through sliding focal adhesions driven by myosin IIA and actin stress fiber dynamics.