S. Wang

This study uses single-cell RNA-seq to analyze human infant retina, identifying cell types, communication networks, and developmental changes, providing a resource for retinal research and regenerative medicine.

This study identifies TMC1 as providing a background leak conductance in mouse auditory hair cells, essential for action potential firing and tonotopic organization.

This study uses single-cell RNA sequencing to analyze the cellular diversity and molecular markers in the retina of a trisomy 21 fetus, revealing communication networks and novel markers.

This study shows that Tomato spotted wilt virus extends the developmental time and increases progeny production in western flower thrips, with a male-biased sex ratio, likely enhancing virus transmission.

The paper identifies cutimycin, an antibiotic produced by Cutibacterium acnes, which reduces Staphylococcus colonization in human skin follicles.

This study shows that inhibiting mTORC1 signaling in aged rats increases muscle mass and reverses sarcopenia-related gene expression changes.

This study compares human and Naegleria CKK domains to show how structural differences in tubulin conformations enable microtubule minus-end recognition.

This study shows that actin filament anchoring to the plasma membrane generates tension in fission yeast cytokinetic rings, explaining constriction dynamics through simulations.

This study investigates whether microbial activity in tropical forests is limited by phosphorus availability, finding that P addition increases soil respiration but suppresses litter decomposition due to organic carbon desorption.

This paper introduces a method to measure single protein properties like size, charge, mobility, and conformational changes using optical imaging and electric fields.

This paper develops a portable 2D gas chromatography device with machine learning to diagnose ARDS from breath samples, achieving 87.1% accuracy.

This study investigates the trade-off between immunity and reproduction in locusts by analyzing transcriptome changes in response to bacterial infection.

The paper identifies core microbiota for flavor production in Chinese liquor fermentation and constructs a synthetic microbiota that replicates natural flavor metabolism and environmental interactions.

This paper introduces a time-resolved digital immunoassay using plasmonic imaging to rapidly and sensitively quantify procalcitonin with a low limit of detection and wide dynamic range.

fluxweb estimates energy fluxes in food webs using a steady-state model and integrates with allometric theory, providing tools for flux calculation and network stability analysis.

This study identifies how SNX16's higher-order assembly regulates endosomal distribution and signaling in neurons, leading to increased synaptic growth.

The paper identifies m6A mRNA methylation as a regulator of erythropoiesis by promoting the translation of key genes involved in erythroid lineage specification.

This paper analyzes an HIV model with latent reservoir and immune impairment, identifying thresholds for post-treatment control and virus rebound based on CTL proliferation rates.

This study shows that vimentin intermediate filaments provide cytoplasmic mechanics that enhance strength, stretchability, resilience, and toughness under severe deformations.

This study shows antibiotic-induced reduction in microbial-derived short-chain fatty acids (SCFAs) in the gut promotes Candida albicans colonization and growth.

This study identifies and analyzes DNA methyltransferase genes in cotton, showing their functional diversity and stress-specific expression patterns.

This study identifies two FDA-approved drugs, lacidipine and phenothrin, as Lassa virus entry inhibitors through high-throughput screening and mechanistic analysis.

This paper shows that RB1 inactivation leads to retinoblastoma in human cone precursors at specific developmental stages, but not in mouse cone precursors, highlighting species-specific differences in tumor genesis.

The paper introduces residue perturbation maps to represent allosteric effects as residue-specific properties using machine learning on molecular dynamics simulations.

This study identifies outer membrane vesicles from Lysobacter enzymogenes C3 as vehicles for delivering antifungal antibiotics to fungal targets.

This paper introduces t-CyCIF, a method for highly multiplexed immunofluorescence imaging of FFPE tissues using conventional microscopes, and demonstrates its application in analyzing tumor antigens and immune markers.

The paper identifies XcpV and XcpW as essential pseudopilin components of the T2SS tip, develops structure-based inhibitory peptides that disrupt the complex and inhibit T2SS in vivo, reducing P. aeruginosa virulence.

This study shows that sublancin enhances macrophage function and protects mice from MRSA infection by activating innate immunity and improving T cell responses.