S. Yamanaka

Fetal Kidney Transplantation for In Utero Fetuses

This paper describes a novel fetal therapy approach using transplanted fetal kidneys from different species to provide a bridge to dialysis in affected fetuses, demonstrating successful urine production and long-term function without immunosuppressants.

Generation of human-pig chimeric renal organoids using iPSC technology

This study generates human-pig chimeric renal organoids using modified human-mouse chimeric methods, demonstrating successful interspecies kidney development.

Effect of Light and Water Agitation on Hatching Processes in Clown Anemonefish Amphiprion ocellaris

This study shows that darkness and water agitation regulate hatching enzyme secretion and chorion digestion in clown anemonefish, enabling synchronized hatching.

A stress-reduced passaging technique improves the viability of human pluripotent cells

This paper introduces a stress-reduced passaging technique for human pluripotent stem cells that improves viability and downstream application efficiency without altering cell characteristics.

HSD11β1 promotes EMT-mediated breast cancer metastasis

This study identifies HSD11β1 as a promoter of breast cancer metastasis via EMT induction and shows that targeting HSD11β1 could suppress metastasis.

The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency

This study shows that ESRG, a HERV-H-driven lncRNA in human pluripotent stem cells, is not required for maintaining or reprogramming pluripotency.

Genome analyses reveal the hybrid origin of the staple food crop white Guinea yam

This study reveals the hybrid origin of white Guinea yam through genomic analysis, showing it arose from crosses between D. praehensilis and D. abyssinica with significant introgression around the SWEETIE gene.

PLZF is a new substrate of CRBN with thalidomide and 5-hydroxythalidomide

The paper identifies PLZF as a CRBN substrate degraded by thalidomide and 5-hydroxythalidomide, linking it to teratogenesis.

Hydrogen Bond Donors and Acceptors are Generally Depolarized in α-Helices as Revealed by a Molecular Tailoring Approach

The paper examines H-bond interaction energies in α-helices using DFT calculations and a molecular tailoring approach, finding weaker energies due to depolarization effects.