X. Liu

The paper investigates how membrane tension affects the size, lifetime, and spatial distribution of clathrin-coated pits during maturation.

This study shows that di-n-butyl phthalate exposure reduces ovarian IGF1 system components and disrupts folliculogenesis in mice.

This study characterizes urine proteomic changes in active and recovered COVID-19 patients, identifying persistent immune and metabolic alterations and potential biomarkers.

This study investigates the role of ALOX15 in lung adenocarcinoma, finding that its downregulation correlates with tumor differentiation, proliferation, and metastasis, and that overexpression inhibits cancer cell growth.

The paper uses multi-omics single-cell data to define the epigenetic basis of castration-resistant prostate luminal cells in mice and identifies key molecular pathways involved.

This study shows that the type VI secretion system in Geobacter metallireducens affects DIET by altering gene expression and electron transfer efficiency.

The paper examines mitogenomic evolutionary rates in Bilateria, finding that parasitism and reduced locomotory capacity are associated with elevated rates, explaining a significant portion of variance in branch lengths.

The paper identifies keystone taxa in activated sludge microbial communities that enhance stability but reduce function, highlighting the trade-off between stability and performance.

This study shows that CXCR2 expression in melanoma progenitor cells drives tumor growth by altering transcriptional programs and immune responses.

This study identifies RIPK3-dependent necroptosis as the main cause of immunodeficiency in RIPK1-deficient rats and suggests necroptosis inhibition as a potential therapy.

The paper identifies palmitoylation of GSDMD at Cys191/Cys192 as essential for its membrane translocation and pore-forming activity in macrophages.

This study shows that extra-islet antigen exposure leads to T-cell exhaustion, which prevents autoimmune diabetes in NOD mice.

This study identifies a comprehensive allergen profile of Blomia tropicalis and validates novel allergens for component-resolved diagnosis of mite allergy.

The paper introduces DBSN, a deep learning method that enables imaging of multiple subcellular structures using only two fluorescent labels, overcoming spectral overlap limitations.

The paper uses SCAP to isolate the WDR76:SPIN1 complex, identifies H3K4me3 binding, and shows its role in DNA damage response through structural modeling and interaction network analysis.

This study clarifies the origin of modern maize by showing it resulted from an ancient admixture between domesticated maize and Zea mays ssp. mexicana around 5300 years ago, contributing to genetic and phenotypic diversity.

This study shows dopamine promotes Klebsiella quasivariicola growth and inflammation in macrophage co-culture, exacerbating lung injury in mice.

This study identifies the role of positively charged residues in helper NLRs for phospholipid binding and plasma membrane association, and shows effector activation induces NRG1 oligomerization at the plasma membrane.

The paper identifies the T813S mutation in the S2 subunit of SARS-CoV Spike protein enhances fusogenicity by improving TMPRSS2 cleavage, increasing viral replication.

This paper develops a mathematical model explaining the evolution of parthenogen fertilization rates and reproductive modes through coevolution of fertilization rate and cell size.

This study shows that high-frequency soil polarization (ECsoil) can accurately measure root volume and distribution in the field, with potential for noninvasive root phenotyping.

This paper introduces a new plant transformation method called RAPID that achieves high efficiency and speed without tissue culture.

This paper describes a novel oncolytic virus encoding a bispecific T-cell engager targeting CEACAM6-expressing tumors, showing enhanced anti-tumor efficacy and safety in vitro and in vivo.

This study shows that reactivation of human endogenous retroviruses during aging promotes cellular senescence and tissue degeneration, and that blocking this reactivation can alleviate aging.

StereoSiTE analyzes spatial transcriptomics data to identify cell-cell interactions in the tumor microenvironment and reveals neutrophil-driven communication networks in treated xenograft models.

This study investigates the deacetylase-dependent and independent roles of HDAC3 in cardiomyopathy using Drosophila, finding it maintains cardiac contractility and prevents Pericardin deposition independently of its deacetylase activity, but regulates triglyceride homeostasis through this activity.

This study shows that an amino acid-enriched elemental diet reduces mucolytic bacteria and protects the mucus layer in mice with colitis.

The paper uses genome and transcriptome data to resolve the phylogeny of chitons, supporting that shell eyes originated in Schizochitonoidea and evolved secondarily in other genera.

The paper sequenced waterbuck genomes to study speciation, finding historical gene flow across a Rift Valley barrier and no reproductive isolation.