X. Liu

This study compares mutational spectra in biofilms of two Bacillus species under abiotic and biotic conditions, finding that smaller population sizes and biotic environments lead to higher mutation rates and diversity.

The paper generates and indexes an EMS mutant library for KN9204 wheat to enhance functional genomics and genetic manipulation for agronomic traits.

The paper improves a centrality algorithm by incorporating protein properties and validates it using yeast networks to study the hepatotoxicity of Pinelliae Rhizoma.

This paper identifies CX3CR1+ CD8+ T cells with low mitochondrial membrane potential as functionally resilient, showing high cytotoxicity and reduced ROS through ME1 upregulation, which enhances their anti-tumor activity.

This study uses a computational model to show that ventricular systolic function affects thrombus formation after EVAR, with specific correlations identified.

The paper analyzes metagenomic and metatranscriptomic data from cold seeps to identify As-cycling genes and microbes, revealing unexpected diversity and functional roles in arsenic transformation.

This paper develops mRNA vaccines against Monkeypox virus that protect mice from lethal infection, with fusion protein vaccines showing better immune responses than separate protein vaccines.

This paper develops a kinetic model for solid waste treatment units using system dynamics and simulation, demonstrating its validity through a 370-day experiment with a prototype.

This study investigates how flow-induced mechanical forces regulate YAP nucleocytoplasmic transport through actin cap formation and nuclear stiffness changes, revealing a unified mechanism linking mechanical stimulation to transcriptional regulation.

The paper evaluates HIV-1 vaccine candidates using HCDR3-engineered B cells, finding that SOSIP-TM mRNA-lipid nanoparticles induce stronger anti-apex responses than multimerized SOSIP proteins.

This study identifies AdgB and AdgI as key proteins in the Variovorax auxin-degradation operon, revealing their roles in IAA uptake and conversion to oxIAA, and demonstrates the operon's potential for IAA regulation in E. coli.

This study investigates the excited-state dynamics of the all-trans protonated retinal Schiff base in CRABPII-based rhodopsin mimics using transient absorption and fluorescence spectroscopy, revealing differences in dynamics across mutants and potential applications in bioimaging.

This study identifies two hydrophobic motifs in VPS37A that bind curved membranes, essential for autophagosome biogenesis.

The paper shows mechanical force induces DRP1-dependent asymmetrical mitochondrial fission, leading to mtDNA-free fragments that recruit Parkin proteins.

The paper identifies divergent electrophile-signaling behaviors between zebrafish Keap1 paralogs using Z-REX, showing zKeap1b promotes Nrf2 signaling while zKeap1a inhibits it.

This study identifies and characterizes circRNAs in moso bamboo, their biogenesis, function, and response to gibberellins and auxins.

This study reveals a comprehensive allergen profile of Tyrophagus putrescentiae using multi-omic approaches, identifying 37 allergen groups and five novel allergens.

The paper demonstrates a genetic method to modify microbial nanowires with peptide ligands to enhance sensor response for specific analytes like ammonia and acetic acid.

This paper introduces FD-DeepLoc, a deep learning method for high-throughput 3D super-resolution imaging over a large field of view using a sCMOS camera.

The paper identifies Zn2+ as a therapeutic agent for calcium oxalate kidney stones by enhancing oxalate-degrading bacteria and their enzymes in the gut microbiota.

This study identifies Naproxen as a chemical inhibitor of PIN auxin transporters in plants, revealing its mechanism of action through cellular, biochemical, and structural analyses.

This study identifies Numb as a ciliary protein that promotes Hedgehog signaling by facilitating Ptch1 exit from the cilium through endocytic mechanisms.

This study presents the structure of the P74-26 bacteriophage tail tube and proposes a model for its assembly mechanism based on cryo-EM data and complementary experiments.

This study identifies ZNF251 haploinsufficiency as a mechanism conferring PARP inhibitor resistance in BRCA1-mutated cancer cells through RAD51-mediated homologous recombination.

This study identifies TRAF6 as a regulator of PD-L1 expression in melanoma through YAP1-TFCP2 signaling, showing TRAF6 inhibition enhances anti-tumor immunity.

This study examines the roles of IFNγ and IL-10 in SARS-CoV-2 infection of rhesus macaques, finding IL-10 suppresses T cell expansion but promotes tissue-resident memory cell formation.

This study investigates the anti-hepatoblastoma effects of the compound AE-848, showing it inhibits cell proliferation, induces apoptosis, and reduces tumor growth in vivo.

This study investigates reductive genome evolution in Cardinium endosymbionts, identifying endogenous plasmids and their enzymes as drivers of genome reduction.

This study uses sedimentary DNA to track past population dynamics of the copepod E. japonicus, finding correlations with in situ production and biomass but not resting eggs or growth rate.

The paper identifies silk-like proteins as the main components of nacre matrix proteins, showing over 90% composition in both soluble and insoluble fractions.