Author

Xandria Johnson

Children's Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

João S. PatrícioiD· 2 shared Lauren G. ZachariasiD· 2 shared Rainah Winston· 2 shared Ralph J. DeBerardinisiD· 2 shared Thomas P. MathewsiD· 2 shared Andrew S. LemoffiD· 1 shared Ashley SolmonsoniD· 1 shared Bailey C. SmithiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

João S. PatrícioORCID

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2 papers

Recent·Most cited

Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice

Milan R. Savani, Bingbing Li, Bailey C. Smith, Wen Gu, Yi Xiao, Gerard Baquer, Tracey E. Shipman, Skyler Oken, Namya Manoj, Lauren G. Zacharias, Vineshkumar Thidil Puliyappadamba, Sylwia A. Stopka, Michael Scott Regan, Michael M. Levitt, Charles K. Edgar, , Samuel K. McBrayer

The paper develops a platform to trace 30 nitrogen isotope-labeled metabolites, revealing cell state-specific pyrimidine synthesis pathway preferences in primitive and differentiated cells.

Nature Metabolism · Apr 29, 2026Peer-reviewedCell Biology

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT

Zheng Wu, Phong T. Nguyen, Varun Sondhi, Run-Wen Yao, Zhifang Lu, Tao Dai, Jui‐Chung Chiang, Feng Cai, Imani M. Williams, Eliot B. Blatt, Zeng‐Fu Shang, Ling Cai, Jing Zhang, Mya D. Moore, Islam Alshamleh, , Ralph J. DeBerardinis

This study identifies NUDT5 as a regulator of purine metabolism and thiopurine sensitivity by interacting with PPAT, independent of its known enzymatic activity.

Science · Nov 6, 2025Peer-reviewedBiochemistry