Author

Rainah Winston

Children's Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Ralph J. DeBerardinisiD· 3 shared Thomas P. MathewsiD· 3 shared João S. PatrícioiD· 2 shared Lauren G. ZachariasiD· 2 shared Trevor S. TippettsiD· 2 shared Xandria Johnson· 2 shared Ákos VégváriiD· 1 shared Alissa Wilhalm· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiochemistry

Ralph J. DeBerardinisORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice

Milan R. Savani, Bingbing Li, Bailey C. Smith, Wen Gu, Yi Xiao, Gerard Baquer, Tracey E. Shipman, Skyler Oken, Namya Manoj, Lauren G. Zacharias, Vineshkumar Thidil Puliyappadamba, Sylwia A. Stopka, Michael Scott Regan, Michael M. Levitt, Charles K. Edgar, , Samuel K. McBrayer

The paper develops a platform to trace 30 nitrogen isotope-labeled metabolites, revealing cell state-specific pyrimidine synthesis pathway preferences in primitive and differentiated cells.

Nature Metabolism · Apr 29, 2026Peer-reviewedCell Biology

MitoSAM-dependent lipoylation controls postnatal heart development via metabolic remodeling

Anastasia Rumyantseva, Alissa Wilhalm, William Carter, Trevor S. Tippetts, Marco F. Moedas, Florian A. Rosenberger, David Moore, Ákos Végvári, Yvonne Hinze, Linden Muellner-Wong, David Alsina, Rolf Wibom, Rainah Winston, Thomas P. Mathews, Lars H. Lund, , Anna Wredenberg

This study shows that mitoSAM-dependent lipoylation is essential for postnatal heart development by enabling metabolic remodeling from glycolysis to oxidative phosphorylation.

bioRxiv · Apr 20, 2026 · PreprintBiochemistry

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT

Zheng Wu, Phong T. Nguyen, Varun Sondhi, Run-Wen Yao, Zhifang Lu, Tao Dai, Jui‐Chung Chiang, Feng Cai, Imani M. Williams, Eliot B. Blatt, Zeng‐Fu Shang, Ling Cai, Jing Zhang, Mya D. Moore, Islam Alshamleh, , Ralph J. DeBerardinis

This study identifies NUDT5 as a regulator of purine metabolism and thiopurine sensitivity by interacting with PPAT, independent of its known enzymatic activity.

Science · Nov 6, 2025Peer-reviewedBiochemistry