Y. Fan

The paper develops SSR markers from drought stress-responsive miRNAs in Dongxiang wild rice and verifies their genetic diversity across DXWR and modern rice varieties.

This study identifies structural features of SPIRAL2 required for its localization and stabilization of microtubule minus ends in plants.

The paper identifies distinct cell adhesion signatures in glioblastoma myeloid-derived suppressor cell subsets, showing that monocytic MDSCs drive tumor growth through enhanced integrin β1 expression.

This study identifies on-target point mutations caused by CRISPR-Cas9 in yeast, showing sequence dependence and involvement of NHEJ components.

This study develops genome-wide lncRNA-derived SSR markers for Dongxiang wild rice and validates their polymorphism and utility in genetic diversity analysis and breeding.

This study identifies that DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junctions, suggesting MMP-9 as a potential therapeutic target for severe dengue.

This study reports a pan-drug-resistant Klebsiella pneumoniae isolate carrying NDM-5 and MCR-8.2 genes, along with chromosomal resistance mechanisms to colistin and tigecycline.

This paper develops a genetic mouse model of MPNST that closely mimics human tumors in genetics, histology, and transcriptome.

This study examines how combining straw returning with potassium fertilizer affects spring maize's lodging resistance, grain quality, and yield in Inner Mongolia.

The paper demonstrates that focused ultrasound activation of the hepatic neural plexus restores glucose homeostasis in diabetes models across multiple species.

This paper discovers CIPS nanosheets that selectively bind SARS-CoV-2 spike protein, inhibit viral entry, and promote macrophage-mediated viral elimination.

This study examines how potassium fertilizer affects dry matter accumulation and potassium absorption in maize inbred lines with different yield types over three years.

This study characterizes intra-tumor heterogeneity across 2,658 human cancer genomes, identifying subclonal mutations and evolutionary patterns across 38 cancer types.

The paper shows that morphogenesis in multi-layered tissues is self-organized by interfacial mechanical interactions that create compression gradients, leading to stratification or 2D morphogenesis depending on tissue fluidity.

This study identifies prognostic non-tumor cell types in glioblastoma by analyzing gene expression across four cohorts, revealing risk and protective factors associated with immune response clusters.

This study uses proteomics to identify complement cascade pathway changes in gastric signet ring cell carcinoma tissues compared to adjacent regions and adenocarcinomas.

The paper shows DNA demethylation of Foxp3 enhancer CNS2 switches transcriptional drivers to maintain Treg identity by stabilizing Foxp3 expression.

The paper identifies four linear B-cell epitopes on the SARS-CoV-2 spike protein that can elicit neutralizing antibodies in multiple species.

The paper investigates functional redundancy in the human microbiome by analyzing genomic content networks and developing a genome evolution model to explain their topological features.

This study identifies DHHC21 as a calcium/calmodulin-dependent enzyme critical for CD4+ T cell activation and differentiation through S-acylation of signaling proteins.

This study identifies cadherin-11 as a mediator of cancer cell hijacking of fibroblasts post-EMT, enhancing invasion and metastasis in solid tumors.

This study identifies S-acylation of ZAP-70 as a T cell receptor-dependent post-translational modification essential for T cell signaling and activation.

The paper investigates how SARS-CoV-2 infection induces epithelial-mesenchymal transition (EMT) in lung cancer models, leading to changes in gene expression and potential therapeutic targets.

The paper shows that BRAFV600E transforming ability depends on the cell of origin's transcriptional program, with neural crest and melanoblasts being more susceptible due to higher chromatin modifying enzyme expression and ATAD2-SOX10 complex formation.

This study shows that ACE2-overexpressed mesenchymal stem cells improve cardiac function and reduce fibrosis in a rat myocardial infarction model.

The paper demonstrates that microbial communities in in-field bioreactors shift dynamically in response to geochemical perturbations, with significant changes in taxa composition and similarity to contaminated well communities.

This paper presents full-length transcriptome data of Ascosphaera apis mycelium and spore using PacBio SMRT sequencing, providing high-quality transcripts for genome and transcriptome annotation improvements.

The paper identifies a plasmid-encoded ter operon in Klebsiella pneumoniae that functions as a microbiome-dependent gut fitness factor, enhancing colonization in the presence of specific gut microbiota.

This study identifies B- and T-cell epitopes from SARS-CoV-2 surface glycoprotein using immune-informatics approaches, confirming their antigenicity and compatibility with HLA alleles for potential vaccine development.