Y. Ma

This study shows that PYY3-36's physiological effects on food intake depend on the vagus nerve's Y2R, but pharmacological effects are not affected.

This study compares the gut DNA and RNA viromes of Chinese residents and Pakistani visitors, finding ethnic origin significantly influences virome composition and diversity.

This study designs and synthesizes potent SARS-CoV-2 main protease inhibitors, with some showing IC50 values below 100 nM and high virus inhibition potency in cell assays.

This study investigates L-arabinose's antifeedant effects on cotton bollworm caterpillars, showing it deters feeding, suppresses gustatory responses, and inhibits sucrase activity.

This paper introduces compressed FLIM for high-speed, high-resolution live-cell imaging, achieving 100 Hz imaging with reduced photobleaching and motion artifacts.

This paper develops an optimal control theory to maximize cooperation in the prisoner's dilemma game by dynamically adjusting payoffs over time, with applications in evolutionary biology and related fields.

This study investigates the effect of hydrogen inhalation on SIgA, PIgR, and cytokines in a COPD rat model, finding improved expression of SIgA and related factors with higher hydrogen concentrations.

IsoMaTrix visualizes isoclines of matrix games and quantifies uncertainty in structured populations, showing spatial configuration impacts cancer model dynamics under treatment.

This paper develops an evolutionary game theory model to design two-drug adaptive chemotherapy schedules that mitigate chemoresistance by leveraging antagonistic drug interactions.

This study investigates how phytochromes in Agrobacterium fabrum affect DNA transfer, growth, swimming, and interbacterial competition, distinguishing light-regulated and light-independent responses.

This study compares non-Cochrane nursing systematic reviews with their PROSPERO-registered protocols, finding widespread discrepancies with few explanations.

This paper develops an oral SARS-COV-2 RBD vaccine using LTB26 adjuvant in mice, showing enhanced antibody production and immune activation through DCs and B cells.

This study shows propionate activates endosomal Gi/p38 signaling via FFA2 to induce GLP-1 release in enteroendocrine cells.

This study investigates the effects of human umbilical cord mesenchymal stem cell transplantation on preserving and restoring fertility in aging and chemotherapy-damaged female mice.

The paper compares immune landscapes in transplant and primary tumors after immunotherapy and radiotherapy, finding that transplant tumors respond better due to CD8+ T cell enrichment.

This study samples ileocecal microbiome in situ using transendoscopic tubing and finds distinct metatranscriptomes compared to fecal samples, diurnal rhythms in bacterial activity, and metabolomic parallels to gut microbiome changes.

This study shows that clustering of CD3ζ chains alone can initiate TCR signaling, including phosphorylation and calcium flux, in reconstituted cells.

This study demonstrates that cross-feeding between Thauera aminoaromatica and Rhodococcus pyridinivorans drives quinoline degradation in a denitrifying bioreactor through 2-hydroxyquinoline as an intermediate.

This study identifies strain-level features of the mouse gut microbiota using metagenome-assembled genomes, revealing distinct genomic and functional characteristics compared to human gut microbes.

This study finds that KALRN mutations enhance anti-tumor immunity and immunotherapy response in cancer by increasing tumor mutation burden and PD-L1 expression.

This paper identifies YdiU as a Mn2+-dependent UMPylase in Salmonella that modulates chaperone function through UMPylation, enhancing stress resistance.

This study isolates and expands SOX9+ renal epithelial cells from adult humans, showing their ability to regenerate kidney tissue in mice.

This paper isolates and characterizes a Rhodopseudomonas palustris strain capable of anaerobically degrading syringic acid, revealing a novel metabolic pathway distinct from the benzoyl-CoA degradation pathway.

This study identifies human lncRNA metabolic regulators (hLMRs) using integrative transcriptome analyses and humanized mouse models, validating one hLMR's role in cholesterol metabolism.

This study shows NDRG2 maintains intestinal epithelial barriers by regulating E-cadherin and adherens junctions, preventing colitis and tumor development.

The paper identifies specific gyrA gene mutations in Mycobacterium tuberculosis isolates that cause discordant levofloxacin resistance between molecular and phenotypic testing.

MACS is a rapid aqueous clearing method that enables 3D imaging of intact organs with high transparency and compatibility with lipophilic dyes.

This study compares the gut microbiome of short-term and long-term medical workers to normal controls, finding significant structural changes linked to hospital exposure.

This study compares the effects of 1-propanol and 2-propanol on DNA structure using fluorescence microscopy and CD measurements, showing different conformational transitions and secondary structure changes.