Y. Song

The study identifies metabolic changes in dormant and after-ripened Korean pine seeds during incubation, showing a larger metabolic switch in dormant seeds after 4 weeks that may help maintain primary physiological dormancy.

Biochemical and transgenic analyses reveal that Petunia hybrida S3-RNase cytotoxicity is largely restricted by a stepwise ubiquitination and degradation pathway during cross-pollination.

This study examines gene expression evolution in Trinidadian guppies during parallel adaptation, finding both plasticity and divergence in transcriptional responses across populations.

This study identifies RBM39's role in promoting PRRSV proliferation by altering c-Jun phosphorylation and binding viral RNA.

This study identifies FERONIA kinase's role in regulating NADPH oxidase to control rhizosphere Pseudomonas levels in Arabidopsis.

This study analyzes fungal communities in Chinese Marselan wine fermentation across regions, finding that environmental factors significantly influence fungal composition and fermentation performance.

This study shows a transdermal patch with physostigmine and procyclidine protects rhesus monkeys against VX intoxication, with 100% protection at 1.5xLD50 and 50xLD50 when combined with atropine and 2-PAM.

This study investigates TREM2 interactions with ApoE and Aβ1-42 using biophysical methods, revealing distinct binding surfaces and a potential role for sTREM2 in inhibiting Aβ polymerization.

This study reveals the molecular architecture of the SARS-CoV-2 virus using cryo-ET and STA, showing the structure of S proteins, N-linked glycans, and RNPs.

Momilactone B inhibits Arabidopsis growth and development by disrupting ABA and auxin signaling, highlighting the role of phytohormones in allelopathic responses.

The paper develops a microfluidic digital immunoassay using machine learning for rapid, multiplexed biomarker detection in clinical samples.

The paper screens siRNA molecules to target SARS-CoV-2 and shows that an RdRp-targeting siRNA reduces infection in hamsters and macaques.

This paper performs population pharmacokinetics analysis of camrelizumab and finds no significant advantage of flat-dose or weight-based dosing regimens.

The paper assesses MCL1 dependence in MDS subtypes and shows that combined inhibition of BCL2 and MCL1 is synergistic in vitro and reduces MDS engraftment in mice.

The paper finds that tropical montane species track temperature increases more effectively than temperate species in two datasets, suggesting a latitudinal gradient in temperature tracking.

This study identifies PSGL-1 as an HIV restriction factor that inhibits HIV DNA synthesis and virion infectivity by restricting actin dynamics and sequestering HIV envelope proteins.

This study identifies Paxillin's role in promoting ATP-induced activation of P2X7 receptor and NLRP3 inflammasome through complex formation and deubiquitination.

The paper improves protein mutational free energy prediction by creating a balanced benchmark set and testing enhancements in the Rosetta software suite.

This study shows that LPS/D-GalN co-administration causes DNA damage in liver cells, with chronic exposure also affecting brain cells, suggesting genotoxic potential.

This study identifies OsNLP4 as a master regulator of nitrogen use efficiency in rice, showing it improves yield and NUE through transcriptional regulation of nitrogen-related genes.

This paper introduces GNEPS, a fluorescent sensor that detects intracellular GTP:GDP ratios in real-time, showing its utility in monitoring metabolic changes across cell types and organelles.

The paper reports the complete genome sequence of a novel BPV type 15 strain from a cow in southern Xinjiang and places it phylogenetically within the Xipapillomavirus genus.

The study shows that millet-based supplements improve gut microbiota diversity in undernourished pigs more effectively than corn-based supplements.

This study identifies and characterizes the kisspeptin system in the sea cucumber Apostichopus japonicus, revealing its existence and function in a non-chordate species.

The paper identifies a miswired enhancer logic driven by PAX3-FOXO1 translocation in rhabdomyosarcoma, disrupting normal transcription factor regulation and promoting undifferentiated proliferation.

This study identifies ISLR as a stromal factor that suppresses epithelial Hippo signaling to promote intestinal regeneration and cancer.

This study shows cediranib inhibits Mycobacterium tuberculosis ClpP1P2 by targeting its equatorial handle domain, revealing conformational changes critical for its function and suggesting a strategy for species-specific inhibitors.

This paper introduces a super-resolution microscope that images whole mammalian cells at ~20 nm 3D resolution, revealing complex cellular structures previously only visible via electron microscopy.

The paper analyzes genomic data from 1,103 Vibrio parahaemolyticus isolates to show recent genetic mixing among four populations due to increased human-mediated dispersal.