N. Zhou

Toward industrial C8 production: Oxygen intrusion drives renewable n caprylate production from ethanol and acetate via intermediate metabolite production

This study identifies oxygen's role in enabling renewable n-caprylate production from ethanol and acetate via intermediate metabolite synthesis in bioreactors.

Genomic characterization of Escherichia coli harbor a polyketide synthase (pks) island associated with colorectal cancer (CRC) development

This study characterizes the genomic distribution and evolution of pks islands in E. coli strains associated with colorectal cancer, revealing phylogenetic patterns and horizontal gene transfer.

RinRK1 Promotes Accumulation of Nod Factor Receptors in Nanodomain-like structures at the tip of infected root hairs

This study identifies RinRK1's role in localizing Nod Factor Receptors to root hair tips through interactions with Flotillin 1, facilitating symbiotic infection.

Metagenome-assembled genomes provide insight into the microbial taxonomy and ecology of the Buhera Soda Pans, Zimbabwe

This study uses metagenomics to reconstruct MAGs from the Buhera Soda Pans, revealing a diverse microbial community dominated by halophilic and haloalkaliphilic bacteria with key metabolic pathways.

Development of a computational model to inform environmental surveillance sampling plans for Salmonella enterica serovar Typhi in wastewater

This paper develops a computational model to predict the probability of detecting Salmonella Typhi in wastewater, aiding in the design of environmental surveillance sampling plans.

Bioorthogonal photocatalytic quinone methide decaging for cell-cell interaction labeling

The paper introduces a method to label and profile cell-cell interactions with high sensitivity and spatial-temporal resolution using a bioorthogonal photocatalytic quinone methide decaging strategy.

Alkaliphilus flagellata sp. nov., Butyricicoccus intestinisimiae sp. nov., Clostridium mobile sp. nov., Clostridium simiarum sp. nov., Dysosmobacter acutus sp. nov., Paenibacillus brevis sp. nov., Peptoniphilus ovalis sp. nov., and Tissierella simiarum sp. nov., isolated from monkey feces

The paper describes eight novel bacterial species isolated from cynomolgus monkey feces and provides their taxonomic characterization.

Unraveling Fe(II)-oxidizing mechanisms in a facultative Fe(II) oxidizer Sideroxydans lithotrophicus ES-1 via culturing, transcriptomics, and RT-qPCR

This study investigates Fe(II) oxidation mechanisms in Sideroxydans lithotrophicus ES-1 using transcriptomics and RT-qPCR, identifying Cyc2 as the Fe(II) oxidase and linking Fe(II) oxidation to carbon fixation.

Oxidized LDL but not angiotensin II induces the interaction between LOX-1 and AT1 receptors

This study shows Ox-LDL, not AngII, induces LOX-1 and AT1-R interaction, leading to cardiomyocyte hypertrophy via Gq protein activation.

Inducing highly physiologically relevant phenotypes of human vascular smooth muscle cells via 3D printing

This study uses 3D printing to create vessel architectures that induce more physiologically relevant phenotypes in vascular smooth muscle cells compared to 2D cultures.

Isolation and Characterization of 2019-nCoV-like Coronavirus from Malayan Pangolins

This study isolates and characterizes a coronavirus from Malayan pangolins that is highly similar to 2019-nCoV, suggesting pangolins may act as an intermediate host.

Existence and functions of hypothalamic kisspeptin neuropeptide signaling system in a non-chordate deuterostome species

This study identifies and characterizes the kisspeptin system in the sea cucumber Apostichopus japonicus, revealing its existence and function in a non-chordate species.

Cooperative pattern formation in multi-species bacterial colonies

This study demonstrates a mechanism for periodic pattern formation in multi-species bacterial colonies through reciprocal density-dependent motility activation.

Abundance and community composition of comammox bacteria in different ecosystems by a universal primer set

This study designs a universal primer set for CAOB amoA genes and reveals their ubiquity and high abundance across diverse ecosystems.

Comparison of tri-exponential decay vs. bi-exponential decay and full fitting vs. segmented fitting for modeling liver intravoxel incoherent motion diffusion MRI

This paper compares bi- and tri-exponential models with full and segmented fitting for IVIM diffusion MRI in healthy livers, finding tri-exponential models provide better fit and improved reproducibility.

RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation

This study identifies RUNX1 and RUNX3 as proteins that protect IKZF1 and IKZF3 from lenalidomide-induced degradation, thereby reducing the effectiveness of lenalidomide in multiple myeloma.

Niacin fine-tunes energy homeostasis through canonical GPR109A signaling

This study shows niacin reduces body weight and fat mass via GPR109A-dependent pathways, improving energy homeostasis in mice.

Crowdsourcing Image Analysis for Plant Phenomics to Generate Ground Truth Data for Machine Learning

This paper evaluates crowdsourcing for generating high-quality ground truth data for machine learning in plant phenomics, finding that Amazon MTurk workers match expert performance.

IVIM parameters have good scan-rescan reproducibility when evidential motion contaminated and poorly fitted image data are removed

The paper assesses IVIM MRI parameter reproducibility after removing motion-contaminated and poorly fitted data, finding good repeatability and reproducibility for Dslow and PF.