Y. Takano

Hydroxyurea inhibits ERAD-L independently of S-phase arrest in budding yeast

This study shows hydroxyurea inhibits ERAD-L in yeast without affecting S-phase arrest or other ERAD pathways.

The establishment of multiple knockout mutants of Colletotrichum orbiculare by CRISPR/Cas9 and Cre/loxP systems

This paper develops CRISPR/Cas9 and Cre/loxP systems to efficiently generate multiple knockout mutants in Colletotrichum orbiculare and identifies functional sugar transporters.

Pathogen-derived 9-methyl sphingoid base is perceived by a lectin receptor kinase in Arabidopsis

The paper shows that oomycete-derived ceramide is cleaved into sphingoid base by ceramidase and recognized by an Arabidopsis receptor kinase, enhancing plant immunity.

Guanosine-specific single-stranded ribonuclease effectors of a phytopathogenic fungus potentiate host immune responses

This study identifies two ribonuclease effectors from a fungal pathogen that induce plant immune responses by cleaving single-stranded RNA at guanosine.

Fungal effector SIB1 of Colletotrichum orbiculare has unique structural features and can suppress plant immunity in Nicotiana benthamiana

This study identifies SIB1, a fungal effector from Colletotrichum orbiculare, which suppresses plant immunity in N. benthamiana by inhibiting ROS and cell death responses.

The Conserved Colletotrichum spp. Effector CEC3 Induces Nuclear Expansion and Cell Death in Plants

This study identifies CEC3 as a conserved effector in Colletotrichum fungi that induces nuclear expansion and cell death in plants, supporting its role in the hemibiotrophic lifestyle.

Year-round dynamics of amplicon sequence variant communities differ among eukaryotes, Mimiviridae, and prokaryotes in a coastal ecosystem

A one-year observation of coastal microbial communities revealed similar but different community dynamics for eukaryotes, a group of large viruses, and prokaryotes.

Lumi-Map, a real-time luciferase bioluminescence screen of mutants combined with MutMap, reveals Arabidopsis genes involved in PAMP-triggered immunity

Lumi-Map combines bioluminescence screening with MutMap to identify Arabidopsis genes involved in PAMP-triggered immunity, revealing three novel PTI-related genes.

RLP23 is required for Arabidopsis immunity against the grey mould pathogen Botrytis cinerea

This study shows RLP23 is essential for Arabidopsis immunity against Botrytis cinerea by recognizing NLP peptides during early infection.

bak1-5 mutation uncouples tryptophan-dependent and independent postinvasive immune pathways triggered in Arabidopsis by multiple fungal pathogens

Isolation of an archaeon at the prokaryote-eukaryote interface

The paper isolates an Asgard archaeon and proposes a symbiosis model for eukaryogenesis based on its morphology and metabolism.

Hydrogen Bond Donors and Acceptors are Generally Depolarized in α-Helices as Revealed by a Molecular Tailoring Approach

The paper examines H-bond interaction energies in α-helices using DFT calculations and a molecular tailoring approach, finding weaker energies due to depolarization effects.