Author

Yan-Ling Zhang

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Deeksha Misri· 2 shared Hasmik KeshishianiD· 2 shared Horia PribiagiD· 2 shared Joshua Z. LeviniD· 2 shared Morgan ShengiD· 2 shared Sean SimmonsiD· 2 shared Steven A. CarriD· 2 shared Alexandra E. GouldiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Deeksha Misri

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The G-protein coupled receptor GPR34 maintains the homeostatic state of microglia and restrains the disease-associated microglial response in an Alzheimers disease model

Ana Geller, Min Jee Kwon, Sean Simmons, Qihong Xu, William E. Martenis, Jordan L. Doman, Sahana Natarajan, Katherine J. Stalnaker, Jixiang Zhang, Xian Adiconis, Trang Nguyen, Matthew Demers, Donovan L. Batzli, Antia Valle-Tojeiro, Christy Biji, , Prabhat S. Kunwar

This study shows that GPR34 maintains microglial homeostasis and limits disease-associated microglial responses in Alzheimer's disease models.

bioRxiv · Nov 26, 2025 · PreprintNeuroscience

Abnormal Lipid Metabolism and Altered Neuronal Support by Astrocytes Lacking Akap11, a Risk Gene for Schizophrenia and Bipolar Disorder

Xiao‐Man Liu, Horia Pribiag, Deeksha Misri, Kwanho Kim, Kira A. Perzel Mandell, Bryan J. Song, David R. Graykowski, Olivia Seidel, Nolan D. Hartley, Mateo Herrera, Haiyun Xu, Matthew Tegtmeyer, Yan-Ling Zhang, Lei Cui, Natalie M. Clark, , Morgan Sheng

This study identifies AKAP11's role in regulating lipid metabolism and neuronal support in astrocytes, linking its dysfunction to schizophrenia and bipolar disorder risk.

bioRxiv · Apr 25, 2025 · PreprintCell Biology