Yonatan Perez

This study identifies cortical tension as a mechanical barrier that prevents premature neuronal differentiation during neurogenesis, showing that reducing it accelerates neuronal lineage commitment and differentiation.

This study uses single-cell analysis of dup15q syndrome to identify developmental and postnatal molecular changes in autism, revealing cell-type specific dysregulation and shared vulnerabilities with idiopathic ASD.

This study shows that the identity of MGE-derived cortical interneurons can be dynamically influenced by their environment, with human 3D models promoting Pvalb expression over Sst.

This study shows that ADGRG1 in microglia helps protect against Alzheimer's disease by improving amyloid clearance and reducing pathology.

The paper constructs a single-cell transcriptomic atlas of human cortical development, identifying lineage and sex-specific gene expression programs linked to autism risk.

This study creates a cross-species proteomic map of synapse development in human, macaque, and mouse neocortex, revealing slower human PSD maturation and its potential link to neoteny.

In primary human cortical tissue and stem cell-derived organoids, SARS-CoV-2 infects astrocytes almost exclusively, apparently through DPP4 rather than ACE2, leaving them reactive and stressed.