Author

Mark W. Youngblood

Northwestern UniversityORCID 0000-0002-1044-8015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Murat GüneliD· 2 shared A. Gulhan Ercan‐SencicekiD· 1 shared Adam M. SonabendiD· 1 shared Amaan Musabji· 1 shared Amy B. HeimbergeriD· 1 shared Arman AfrasiyabiiD· 1 shared Atique U. AhmediD· 1 shared Aurora Lopez‐RosasiD· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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2 shared papersCancer Biology

Murat GünelORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Myeloid-targeted RNA nanotherapeutics rewire cholesterol metabolism to unleash anti-tumor immunity in glioblastoma

Jiawei Huo, Hanchen Lin, Yinmeng Li, Shashwat Tripathi, Rafał Chojak, Caylee Silvers, Yirui Peng, Lauren K. Boland, Jianzhong Zhang, Kathleen McCortney, Rasangi M. Perera, Hinda Najem, Leah K. Billingham, Tzu-Yi Chia, Xiaoyang Chen, , Peng Zhang

The paper develops RNA nanotherapeutics targeting TAMC cholesterol metabolism to enhance anti-tumor immunity in glioblastoma.

bioRxiv · Aug 7, 2026 · PreprintImmunology

Multicellular Spatial Programs Define the Histopathological Architecture of Meningioma

Danielle F. Miyagishima, Arman Afrasiyabi, Declan McGuone, Zeynep Erson-Omay, Kanat Yalcin, Yutaka Takeo, Phan Q. Duy, Batur Gültekin, Jacky Yeung, A. Gulhan Ercan‐Sencicek, Octavian Henegariu, Mark W. Youngblood, Ketu Mishra-Gorur, Katsuhito Yasuno, Guilin Wang, , Murat Günel

This study identifies multicellular spatial molecular programs in meningiomas using multi-omic data and develops a model to infer these programs from histopathology.

bioRxiv · Jun 17, 2026 · PreprintCancer Biology

Direct in vivo mapping of functional suppressors in glioblastoma genome

Ryan Dz-Wei Chow, Christopher D. Guzman, Guangchuan Wang, Florian Schmidt, Mark W. Youngblood, Lupeng Ye, Youssef Errami, Matthew B. Dong, Michael A. Q. Martinez, Sensen Zhang, Paul A. Renauer, Kaya Bilgüvar, Murat Günel, Phillip A. Sharp, Feng Zhang, , Sidi Chen

This study uses an AAV-mediated CRISPR screen in mice to identify functional suppressors of glioblastoma, revealing novel and canonical tumor suppressors and their interactions.

bioRxiv · Jun 22, 2017 · PreprintSystems Biology