Author

Minjun Li

Chinese Academy of SciencesORCID 0000-0002-4382-5585Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Adrienne Ann BoireiD· 2 shared Ana Rita NobreiD· 2 shared Branavan ManoranjaniD· 2 shared Haixia SuiD· 2 shared Ján RemšíkiD· 2 shared Jenna SnyderiD· 2 shared Kiana ChabotiD· 2 shared Sofia Piedrafita-OrtiziD· 2 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Adrienne Ann BoireORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Autocrine CXCL1-CXCR2 Signaling Mediates Leptomeningeal Resistance to Radiation Therapy

Ahmed M. Osman, Ján Remšík, Jenna Snyder, Neil Ari Wijetunga, Branavan Manoranjan, Ana Rita Nobre, Morgan E. Freret, David Guber, Kiana Chabot, Sofia Piedrafita-Ortiz, Xinran Tong, Helen G. Wang, Minjun Li, Andrew Jeffrey Dunbar, Ross L. Levine, , Adrienne Ann Boire

The paper identifies CXCL1-CXCR2 signaling as a mediator of leptomeningeal metastasis resistance to radiation therapy and presents it as a potential therapeutic target.

bioRxiv · Feb 20, 2025 · PreprintCancer Biology

Retinoid X Receptor Signaling Mediates Cancer Cell Lipid Metabolism in the Leptomeninges

Xinran Tong, Ján Remšík, Jeannette R. Brook, Boryana Petrova, Lele Xu, Minjun Li, Jenna Snyder, Kiana Chabot, Rachel Estrera, Isaiah Osei-Gyening, Ana Rita Nobre, Helen H. Wang, Ahmed Osman, Alan Y. L. Wong, Mega Sidharta, , Adrienne Ann Boire

This study identifies RXR signaling as a mediator of lipid metabolism in leptomeningeal metastatic cancer cells, revealing a potential therapeutic target.

bioRxiv · Oct 13, 2024 · PreprintCancer Biology

Identification of C270 as a novel site for allosteric modulators of SARS-CoV-2 papain-like protease

Hangchen Hu, Qian Wang, Haixia Su, Qiang Shao, Wenfeng Zhao, Guofeng Chen, Minjun Li, Yechun Xu

The paper identifies C270 as a novel allosteric site for modulators of SARS-CoV-2 PLpro, revealing a mechanism for covalent activation and inhibition.

bioRxiv · Mar 30, 2022 · PreprintMolecular Biology

Discovery of baicalin and baicalein as novel, natural product inhibitors of SARS-CoV-2 3CL protease in vitro

Haixia Su, Sheng Yao, Wenfeng Zhao, Minjun Li, Jia Liu, Weijuan Shang, Hang Xie, Chang‐Qiang Ke, Mei-na Gao, Kunqian Yu, Hong Shu Liu, Jingshan Shen, Wei Tang, Leike Zhang, Jianping Zuo, , Yechun Xu

Baicalin and baicalein from Scutellaria baicalensis inhibit SARS-CoV-2 3CL protease non-covalently; a 2.2 Å baicalein complex structure shows an unusual shield-like binding mode.

bioRxiv · Apr 13, 2020 · PreprintMolecular Biology✦ In-depth digest