Kim Remans

Molecular co-accessibility identifies coordinated regulation between distant cis-regulatory elements

The paper quantifies co-accessibility between cis-regulatory elements in Drosophila using single-molecule footprinting and long-read sequencing, revealing coordinated regulation across genomic distances.

Short linear motifs - Underexplored players driving Toxoplasma gondii infection

The paper identifies short linear motifs in Toxoplasma gondii secreted proteins using a computational pipeline and validates some predictions experimentally.

AlphaDesign: A de novo protein design framework based on AlphaFold

AlphaDesign uses AlphaFold to design novel protein structures, including monomers, dimers, and higher-order complexes, showing structural integrity and conformational switching capabilities.

Selection-free CRISPR-Cas9 editing protocol for distant Dictyostelid species

This paper introduces a selection-free CRISPR-Cas9 editing protocol effective across multiple Dictyostelid species, enabling efficient knock-out and knock-in mutations without antibiotic selection.

Trim66 paternal deficiency causes intrauterine overgrowth

This study shows that Trim66 deficiency in male mice leads to paternal transmission of intrauterine overgrowth in offspring.

Sbh1/Sec61beta is a specific signal peptide receptor within the Sec61 channel

This study identifies Sbh1/Sec61β as a specific signal peptide receptor that recognizes and guides substrates into the Sec61 channel through its cytosolic IDR and conserved regions.

Extensive OMICS resource for Sf21 and Tni cell lines

The paper presents genome assemblies and gene predictions for Sf21 and Tni cell lines using multi-omics data, enabling improved use in protein expression and genome engineering.