Author

William S. Foster

Babraham InstituteORCID 0000-0002-7103-3657Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alex J. WhaleiD· 1 shared Amanda W. LundiD· 1 shared Andrew David MilleriD· 1 shared Carla R. NowosadiD· 1 shared Clare M. LloydiD· 1 shared Daniel James HodsoniD· 1 shared Davide Maria VespasianiiD· 1 shared Dimitri Kakabadse· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

Alex J. WhaleORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Lymphatic constraint of germinal centers optimizes protective antibody responses

Tenny Mudianto, Gabrielle R. Berman, Kimberly S. Zaldana, Marta Schips, Niklas Schwan, Luan Firmino-Cruz, Jana Bilanovic, Ochapa Ibrahim, Vanessa Cristaldi, William S. Foster, Lina Fikri, Sabrina M. Solis, Han M. Chen, Dimitri Kakabadse, Michael Cammer, , Amanda W. Lund

This study shows that lymphatic remodeling in skin and lymph nodes constrains germinal center size and function to optimize protective antibody responses during viral infection.

Immunity · Oct 1, 2026Peer-reviewedImmunology

RNA-binding proteins control the G2-M checkpoint of the germinal centre B cell

Fiamma Salerno, Alex J. Whale, Louise S. Matheson, Davide Maria Vespasiani, William S. Foster, Twm J. Mitchell, Michael Screen, Melanie Stammers, Sarah E. Bell, Daniel James Hodson, Hamish W. King, Michelle A. Linterman, Jonathan M. Houseley, Martin Turner

This study identifies ZFP36L1 and ZFP36L2 as RNA-binding proteins that regulate the G2-M checkpoint in GC B cells to prevent replication stress and maintain genome stability.

Science Immunology · Oct 31, 2025Peer-reviewedImmunology

Differentiation of human T follicular helper cells in vitro requires co-operation between STAT3 and SMAD signaling cytokines that is restrained by IL-2

William S. Foster, Lucía Labeur-Iurman, Geoffrey S. Williams, Matthew J. Robinson, Gianluca Carlesso, Clare M. Lloyd, James A. Harker

This study shows that human T follicular helper cells differentiate in vitro through STAT3 and SMAD cytokine cooperation, but IL-2 inhibits this process.

bioRxiv · Jan 12, 2025 · PreprintImmunology