Viola M. J. Oorschot

Microtubules sustain the fidelity of cellularization in a coenocytic relative of animals

This study investigates cellularization in Sphaeroforma arctica, showing microtubules help guide plasma membrane furrows to ensure equal partitioning of nuclei and cytoplasm during division.

Selective autophagy of whole micronuclei suppresses chromosomal instability

The paper shows that autophagy selectively degrades micronuclei with nuclear envelope defects, preventing chromosomal instability by eliminating missegregated chromosomal material.

In-cell structure and snapshots of copia retrotransposons in intact tissue by cryo-electron tomography

This study uses cryo-ET to visualize copia retrotransposon structure in Drosophila cells, revealing nuclear clustering and size selection during gametogenesis.

Sprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in humans

This study compares mitochondrial remodelling in humans after moderate-intensity continuous exercise and sprint-interval exercise, showing divergent adaptations in mitochondrial structure, function, and protein expression.

Myelin and nodal plasticity modulate action potential conduction in the adult mouse brain

The paper shows that mature myelin in adult mice is plastic and can modify node of Ranvier length and periaxonal space size to adjust action potential conduction velocity and synchronicity.

Metformin rescues muscle function in BAG3 myofibrillar myopathy models

This study identifies Metformin as a potential therapy for BAG3 myofibrillar myopathy by rescuing muscle function in zebrafish models and reducing protein aggregates in human cells.