Gut microbiota and health

The paper uses metabolic modeling of chicken cecal microbiomes to show how Bacteroides fragilis influences community metabolism and how its absence leads to functional reconfiguration and disease-like profiles.

This study examines how four immunosuppressants alter the gut microbiome and immune responses over time, revealing drug-specific and tissue-dependent effects on microbial composition and lymphoid architecture.

The paper investigates how spatial constraints and enzyme composition regulate amylosome-mediated resistant starch degradation by Ruminococcus bromii in the human colon.

This study investigates the off-target antibacterial effects of 1076 industrial and agricultural chemicals on 22 human gut bacteria, revealing 588 previously unreported interactions.

The paper uses deep learning to identify three functional archetypes in the adult human gut microbiome, revealing their roles in interindividual variability and disease associations.

This paper uses gnotobiotic mice to model microbiome repair effects in undernourished children, revealing changes in gut cell function and microbial gene expression.

The paper identifies microbiome markers in primary colorectal cancer tumors that predict distant metastasis risk using cohort data and molecular techniques.

This study links the infant gut microbiome and resistome to bacterial strains in mother's milk using metagenomic samples from mother-infant pairs.

This study identifies host genetic variants linked to Lactiplantibacillus plantarum abundance in Drosophila melanogaster and shows heparan sulfate synthesis promotes microbiota expansion and intestinal defense during infection.

The paper develops gut microbial functional pathway scores from metatranscriptome data to identify molecular markers associated with irritable bowel syndrome and its subtypes.

The paper uses ME-models to predict proteome allocation in the gut microbiome and identifies taxa associated with metabolic changes in IBD patients.

This study shows that cerebral ischaemic stroke alters mucosal IgA responses and host-commensal microbiota interactions, leading to changes in intestinal microbiota composition.

This study links gut microbiota composition to personality traits in captive common marmosets, finding specific bacterial taxa associated with behavioral characteristics.

This study shows that Arpc5-containing Arp2/3 complexes are critical for macrophage function and maintaining host-microbiota homeostasis, as their loss leads to intestinal inflammation.

The paper examines gut microbiome variation in juvenile blue tits across urban, suburban, and natural habitats in Warsaw, finding reduced diversity in urban areas and year-dependent effects.

This study examines the effects of oral Chlamydia vaccination on gut microbiome and metabolite composition, identifying microbial and metabolic changes and potential biomarkers of immunization.

This study characterizes the gut and gastric residuals microbiome in preterm infants, identifying distinct microbial clusters and dynamics associated with clinical outcomes.

This study shows that a Muc2 mutation in Winnie mice leads to colitis-associated tumorigenesis driven by the gut microbiome and metabolome, with SPF conditions promoting severe disease and CAC.

The paper shows that nutrient competition drives changes in gut microbiome composition under drug perturbations, with implications for predicting and mitigating drug side effects.

This study shows that perinatal morphine exposure in rats causes long-term intestinal microbiota changes that may affect immune system development and increase infection risk.

The paper presents a gut microbiome dataset from Indonesia, revealing novel species and subspecies linked to rural-to-urban lifestyle transitions and showing that community-level diet differences drive microbiome divergence.

The paper constructs a comprehensive gut microbiome reference database from Chinese and non-Chinese populations, revealing population-specific microbial features linked to host physiology.

This study shows that bacterial species and individual donors differentially modulate airway gene expression and alternative splicing in human epithelial cells.

The paper examines indirect environmental effects on the gut-brain axis in Siberian flying squirrels, finding age-dependent impacts on gut microbiota via glucocorticoids.

This study shows that microbial succession during weaning is driven by the ability of microbes to metabolize host glycans, using a mouse model and genomic analysis.

This study shows maternal undernutrition worsens growth stunting in offspring through microbiota-dependent mechanisms, highlighting the need for interventions targeting both mothers and children.

This study shows high-altitude mountaineering alters gut microbiome composition and function, linked to dietary intake and performance markers in alpinists.

The paper identifies oxalotrophy as a rare metabolic trait in the human microbiome, primarily confined to the gut, and finds evidence of horizontal gene transfer for the trait.

Gut3Gel is a new in vitro mucus model that supports diverse intestinal microbiota growth and metabolic activity, offering a scalable platform for microbiota research.

This study identifies the group B [FeFe]-hydrogenase as the primary enzyme driving fermentative H2 production in the human gut, linking it to gut health and disease.