Olfactory and Sensory Function Studies

Neurotransmitter regulation rather than cell-intrinsic properties shape the high-pass filtering properties of olfactory bulb glomeruli

The paper tests a high-pass filtering model in olfactory bulb glomeruli by comparing PG cells and eTCs, finding that PG cells are not more responsive to weak stimuli than eTCs.

Paradoxical relationship between speed and accuracy in olfactory figure-background segregation

The paper investigates how background odors affect odor detection speed and accuracy in mice, finding that background odors add noise to decision-making, reducing accuracy while increasing speed.

Transcriptional adaptation of sensory neurons to GPCR identity and activity

The paper investigates how olfactory sensory neurons adapt transcriptionally to GPCR identity and activity, finding that receptor-specific transcriptomic profiles change with odorant exposure.

Parallel processing by distinct classes of principal neurons in the olfactory cortex

The paper investigates the roles of two neuron types in the olfactory cortex and finds they process odor information in parallel rather than sequentially.

Sniffing the Human Body-Volatile Hexadecanal Blocks Aggression in Men but Triggers Aggression in Women

This study investigates the effect of hexadecanal, a human body-volatile, on aggression in men and women, finding it blocks aggression in men but triggers it in women.

Optical manipulations reveal strong reciprocal inhibition but limited recurrent excitation within olfactory bulb glomeruli

The paper investigates synaptic connections within olfactory bulb glomeruli and finds strong inhibition from PG cells to eTCs but limited direct excitation between eTCs and PG cells.

Balancing memory fidelity and representational stability in the female mouse accessory olfactory bulb

The paper investigates how female mice balance memory fidelity and representational stability in the accessory olfactory bulb during the Bruce Effect by analyzing neuronal responses to odorants before and after imprinting.

Circuit contributions to sensory-driven glutamatergic drive of olfactory bulb mitral and tufted cells during odorant inhalation

The paper investigates the contribution of direct and indirect glutamatergic inputs to mitral/tufted cells in the olfactory bulb during odorant inhalation, finding that direct OSN input dominates and shapes temporal dynamics.

Cholinergic modulation of distinct inhibitory domains in granule cells of the olfactory bulb

The paper investigates how acetylcholine modulates inhibitory inputs to granule cells in the olfactory bulb, showing distinct effects on proximal and distal inhibition through muscarinic receptor activation.

Cortical feedback and gating in odor discrimination and generalization

The paper proposes a statistical mechanism for how context changes odor perception through feedback and cortical gating, predicting convergence and divergence trends based on odor similarity.

Self-grooming promotes social attraction in mice via chemosensory communication

The paper shows that self-grooming in mice increases social attraction through chemosensory cues, using optogenetic induction of grooming behavior.

Non-invasive diagnostic method to objectively measure olfaction and diagnose smell disorders by molecularly targeted fluorescent imaging agent

This paper develops a non-invasive fluorescent imaging agent to objectively measure olfaction loss by targeting NaV1.7, showing correlation between fluorescence intensity and smell loss severity.

Distinct interhemispheric connectivity at the level of the olfactory bulb emerges during Xenopus laevis metamorphosis

This study examines how olfactory connectivity changes during Xenopus laevis metamorphosis, revealing distinct functional streams in the olfactory bulb that remain intact despite structural remodeling.

Analyzing the differences in olfactory bulb mitral cell spiking with ortho- and retronasal stimulation

This study compares spiking patterns in rat olfactory bulb mitral cells under ortho- and retronasal stimulation, finding differences in firing rates and spike covariances, and develops models to explain these differences.

Decoding the olfactory map: targeted transcriptomics link olfactory sensory neurons to glomeruli

The paper spatially maps olfactory receptors to glomeruli in the mouse olfactory bulb using targeted transcriptomics.

What the odor is not: Estimation by elimination

The paper introduces a decoding method for olfactory systems by focusing on non-responsive receptors to identify what an odor is not, improving accuracy in determining odorants and their concentrations.

Functional relevance of dual olfactory bulb in olfactory coding

This study uses optogenetics and behavioral experiments in mice to show that each olfactory bulb contributes distinct information and that mice integrate this information to identify odors.

Multimodal Learning of Pheromone Locations

This study shows that female mice can memorize pheromone locations using both olfactory and somatosensory systems, but not when either system is blocked or pheromonal cues are replaced with same-sex cues.

Acquired olfactory loss alters functional connectivity and morphology

This study examines how recent acquired olfactory loss affects cerebral morphology and functional connectivity in humans.

The olfactory bulb contributes to the adaptation of odor responses: the input-output transformation

The paper investigates whether the olfactory bulb contributes to odor response adaptation by comparing input and output signals in the olfactory bulb during repeated odor stimulation.

Odor-evoked Increases in Olfactory Bulb Mitral Cell Spiking Variability

The paper shows that olfactory bulb mitral cells exhibit increased spiking variability at stimulus onset, contrasting with the commonly observed decrease in cortical systems.

Molecular characterization of projection neuron subtypes in the mouse olfactory bulb

The paper identifies molecular markers and gene regulatory mechanisms for projection neuron subtypes in the mouse olfactory bulb using single nucleus and bulk RNA sequencing.

Volumetric alteration of olfactory bulb and immune-related molecular changes in olfactory epithelium in first episode psychosis patients

This study finds reduced olfactory bulb volume and immune-related molecular changes in olfactory epithelium of first episode psychosis patients, linking nasal factors to brain structural changes.

Age-dependent appearance of SARS-CoV-2 entry cells in mouse chemosensory systems reflects COVID-19 anosmia and ageusia symptoms.

The paper identifies age-dependent appearance of ACE2/TMPRSS2-expressing cells in mouse chemosensory systems, linking them to COVID-19 anosmia and ageusia symptoms.

Coordination of two enhancers drives expression of olfactory trace amine-associated receptors

The paper identifies two enhancers critical for TAAR gene expression in olfactory sensory neurons and shows they operate in cis to regulate gene choice.

Sniffing Out New Friends: Similarity in Body-Odor Predicts the Quality of Same-Sex Non-Romantic Dyadic Interactions

The paper finds that body-odor similarity predicts better same-sex non-romantic dyadic interactions using electronic nose and human smell ratings.

A physicochemical model of odor sampling

The paper develops a physicochemical model of odor sampling that simulates ligand-receptor interactions and evaluates their impact on odor discrimination sensitivity.

The influence of stimulus duration on olfactory identity

This study investigates how stimulus duration affects olfactory identity in mice by using optogenetic activation and behavioral assessment.

Representational drift in primary olfactory cortex

This study shows that odor representations in the mouse piriform cortex drift over time, reducing classifier performance, and that continuous odor exposure slows but does not eliminate this drift.

Neural Activation in the Olfactory Epithelium of the East African Cichlid (Haplochromis chilotes) in Response to Odorant Exposure

This study investigates neural activation patterns in the olfactory epithelium of East African cichlids in response to odorants, revealing receptor-specific responses to amino acids and steroids.