Neuroendocrine regulation and behavior

The paper identifies two distinct amygdala cell populations in male mice with different roles in social behavior, showing that MeAFoxp2 cells are specialized for male conspecific cues and aggression, while MeADbx1 cells respond broadly to social cues.

The paper quantifies brain and plasma steroids in non-breeding electric fish to explore their role in aggression, finding sex-specific differences and estrogenic involvement.

This study investigates the role of the basolateral amygdala and insular cortex in social affective behavior in female rats, finding that these regions are necessary for appropriate social affective responses.

The paper identifies a neural circuit in mice that links infant cries to oxytocin neuron activation, showing how auditory cues influence maternal behavior through thalamic input.

The paper investigates neural dynamics in the limbic system of male mice during sexual and aggressive behaviors, identifying distinct network states associated with each behavior.

The paper examines transcription and DNA methylation differences in prairie vole hippocampal dentate gyrus across four behavioral groups, finding gene expression and methylation changes linked to paternal behavior.

This study shows that perinatal morphine exposure reduces social play in adolescent female rats, possibly due to altered oxytocin signaling in the nucleus accumbens.

The paper identifies a sex-dependent neural circuit from the locus coeruleus to the anterior cingulate cortex that modulates parental care in mice by influencing pup retrieval behavior.

The paper develops a Cre-free method to monitor oxytocin neuron activity in lactating mice and shows that pulsatile activity depends on mother-pup contact.

This study examines how parental behavior and vasopressin neuron counts in prairie voles change with pup age, co-parenting, and acute stress, showing experience-dependent plasticity.

This study shows that testosterone reduces strategic prosocial behavior in males when they are being watched, without affecting reinforcement learning itself.

The paper shows that human endogenous oxytocin responses to social touch adapt based on recent social context, influencing both hormonal and neural activity.

The paper shows that prolonged partner separation reduces transcriptional signatures of pair bonding in male prairie voles, despite persistent behavioral traits.

The paper develops a new oxytocin sensor to study compartmental OT release in neurons and finds distinct calcium channel roles and fusion machinery differences in axons and somatodendritic regions.

This study investigates how activating the lateral septum in male prairie voles affects prosocial and antisocial behaviors, finding it increases affiliative behaviors and reduces selective aggression without altering partner preferences.

This study examines the oxytocin system and OTR-expressing astrocytes in a mouse model of PWS, finding reduced oxytocin cells and OTR-expressing astrocytes in specific brain regions with sex-specific differences.

This study shows that prolactin is necessary for paternal behavior in male mice, acting through CaMKII-expressing neurons, similar to its role in maternal behavior.

This paper introduces a fluorescent sensor for real-time measurement of extracellular oxytocin dynamics in the brain and identifies rhythmic changes in OT levels.

The paper identifies a neural circuit involving the NLOT that links the SON-AVP system to neocortical regions, promoting social behavior under osmotic stress.

The paper identifies a thalamo-preoptic pathway that controls social touch by bypassing the cerebral cortex, involving PTH2-expressing neurons and a conserved circuit across species.

This study examines how oxytocin modulates social brain network correlations during resting and task states using fMRI, finding that OT increases predictive power of resting state networks for task-evoked activity and reduces individual variation.

The paper records and manipulates maternal oxytocin (OT) neural activities in mice using fiber photometry and identifies plasticity and modulatory circuits.

This study shows that oxytocin excites glutamatergic neurons in the endopiriform nucleus of juvenile mice through OXTR signaling.

This study shows that oxytocin's effect on stress-related brain pathways in humans is reduced when serotonin signaling is decreased, suggesting a mediating role for serotonin.

This study maps the whole-brain connectivity of oxytocin neurons in mice, revealing distinct roles of paraventricular and supraoptic OT neurons in circuit-specific functions.

This study shows that cesarean delivery in prairie voles leads to long-term social and physiological changes, including impaired partner preference formation, which can be reversed with oxytocin treatment.

The paper investigates changes in the PVN-to-CA2 oxytocin pathway in heart failure rats, finding altered oxytocinergic innervation and reduced OTR-expressing astrocytes.

This paper introduces a novel animal model, the sexual aggression test (SxAT), to study sexual aggression in male rats and identifies neural correlates of the behavior.

This study examines chronic intranasal oxytocin's effects on neuroanatomy and behavior in three autism-related mouse models, finding limited effects and no consistent response patterns.