Evolution and Genetic Dynamics

Elevated rates and biased spectra of mutations in anaerobically cultured lactic acid bacteria

This study measures mutation rates and spectra in anaerobic lactic acid bacteria over 1000 generations, revealing elevated rates and transition biases, with novel mutation dynamics in specific species.

Ecological stoichiometry and life history theory, not the identity of genomic variants, predict rapid adaptation

This study shows ecological stoichiometry and life history theory predict phenotypic adaptation in Drosophila, while genomic data fail to predict the SNPs and genes involved.

Can evolutionary potential help plants survive climate change? High variability in evolvability and G-matrix structure of Hypericum populations

The paper compares evolutionary potential and G-matrix structure across populations of two Hypericum species to assess genetic stability and trait modularity under climate change.

Fluctuating Selection among Individuals (FSI) as a Novel Genetic Drift in Molecular Evolution

The paper introduces Fluctuating Selection among Individuals (FSI) as a new form of genetic drift, showing it dominates molecular evolution in most metazoan species.

A higher load of deleterious mutations has a detrimental effect on tree growth in maritime pine

This study shows that higher genetic load, caused by deleterious mutations, is associated with reduced tree growth in maritime pine.

Predicting Hybrid Fitness: the Effects of Ploidy and Complex Ancestry

The paper introduces a fitness landscape model to predict hybrid fitness across varying ploidy and lineage complexity, validated using maize and rye hybrid data.

Structure-informed evolutionary analysis of the meiotic recombination machinery

The paper analyzes evolutionary divergence in meiotic recombination proteins across four taxa, identifying regions under positive selection and functional constraints using structural and functional data.

Cryptic multicellularity in wild yeast brings selective advantages under stress

This study identifies a cryptic multicellular trait in wild yeast that provides survival advantages under stress conditions.

Community coalescence reveals strong selection and coexistence within species in complex microbial communities

The paper studies intra-species diversity in microbial communities by competing gut strains, finding strong selection and coexistence due to biotic interactions.

Evolution toward larger cell size reduces internal cellular density

This study shows that evolving larger cell size reduces internal cellular density, as material accumulation does not keep pace with volume increase, both in experimental evolution and across species.

High-resolution mapping of a rapidly evolving complex trait reveals genotype-phenotype stability and an unpredictable genetic architecture of adaptation

This study maps the genetic architecture of pigmentation evolution in Drosophila melanogaster and finds that while trait direction can be predicted, the specific loci involved are unpredictable and the genotype-phenotype map is stable across populations.

Migration load, competition, and metabolic trade-offs shape spatial divergence through eco-evolutionary dynamics

This study shows how migration, competition, and metabolic trade-offs influence spatial divergence in Lactococcus cremoris through eco-evolutionary feedbacks.

Additivity of the genetic load is a product of both synergistic and antagonistic epistasis in Drosophila

The paper investigates epistatic interactions in Drosophila by analyzing inbreeding effects on pupal productivity and pupa-to-adult viability, finding synergistic and antagonistic epistasis in different traits.

Delineating Mutation Bias and Selection during Plant Development

The paper develops a framework to distinguish mutation bias from selection in plants by analyzing mutation spectra and genome architecture, revealing reduced mutation rates in gene bodies and broadly expressed genes.

Community complexity does not weaken pairwise coevolution in a soil bacterial community

The study examines how community complexity affects coevolution between Pseudomonas fluorescens and Variovorax sp., finding that pairwise coevolution remains unaffected by the presence of other species.

Dynamical memory underlies prolonged plasmid persistence after transient antibiotic treatment

The paper shows that prolonged plasmid persistence after antibiotic treatment is due to dynamical memory, not horizontal transfer or low plasmid cost.

Experimental evolution of gene essentiality in bacteria

The paper generates essential gene deletion mutants in Streptococcus sanguinis and identifies suppressor mutations through experimental evolution, revealing new gene and pathway relationships.

Coevolutionary cycling in allele frequencies and the evolution of virulence

This study investigates how coevolutionary cycling in allele frequencies affects virulence evolution in a free-living parasite using population and quantitative genetic approaches.

Environmental Heterogeneity Altered the Growth Fitness of Antibiotic-Resistant Mutants and the Resistance Prevalence in Escherichia coli populations

This study identifies environmental factors affecting the growth fitness of antibiotic-resistant Escherichia coli mutants and their resistance prevalence.

Environment by environment interactions (ExE) differ across genetic backgrounds (ExExG)

The paper investigates environment-by-environment interactions (ExE) across genetic backgrounds (ExExG) in yeast, showing that drug combinations vary in effectiveness among mutants and introducing a new predictive framework.

Comparative and population genomics analyses of the regulatory Transcription Factor (TF)-DNA interaction

This study uses population and comparative genomics to analyze how natural selection affects TF-DNA interaction motifs, finding purifying selection on TF-BDs and increased positive selection in species with large Ne.

Estimating the additive genetic variance for relative fitness from changes in allele frequency

This paper introduces a method to estimate additive genetic variance for relative fitness by tracking population genetic changes, avoiding direct fitness measurements.

Maintenance of polymorphism in spatially heterogeneous environments

The paper develops a theoretical method to analyze complex spatially heterogeneous population models and shows that high environmental spatial autocorrelation promotes the maintenance of locally adaptive alleles.

Fitness at the Expanding Front: An Exploration-Exploitation Trade-off in Phenotypic Switching

The paper investigates how phenotypic switching strategies affect expansion speed in spatial populations, showing optimal switching rates and the impact of adaptation lags and spatial structure.

Are mitochondrial DNA mutations under purifying selection in somatic tissues?

The paper reanalyzes mtDNA mutation data to determine if somatic mutations are under purifying selection, finding that apparent selection signals are due to germline mutations and most somatic mutations are neutral.

Quantifying the fitness contribution of phagocytosis

The paper develops a mathematical model to quantify the fitness benefits of phagocytosis in evolutionary contexts and identifies conditions under which it provides an advantage.

Evolutionary dynamics of the tgr gene family in Dictyostelium allows escape from Crozier's Paradox

The paper examines Crozier's Paradox in Dictyostelium discoideum by analyzing tgrB1 and tgrC1 genes, finding no strong evidence for the paradox and suggesting recombination generates genetic variation.

A general model for genomic traits evolution

The paper develops a general model for genomic trait evolution that explains dynamics across diverse taxa and fits experimental and observational data.

TyCHE enables time-resolved lineage tracing of heterogeneously-evolving populations

TyCHE improves time-resolved lineage tracing by accounting for heterogeneous mutation rates, applied to memory B cells, germinal centers, gliomas, and bacterial infections.

Evolutionary branching points in multi-dimensional trait spaces

This paper extends evolutionary branching theory to multi-dimensional trait spaces by introducing branching possibility and inevitability criteria, showing they can induce branching under both asexual and sexual reproduction.