Hippo pathway signaling and YAP/TAZ

Amot regulates neuronal dendritic tree through Yap1

This study shows Amot and Yap1 regulate dendritic tree morphogenesis in neurons, with Amot mediating this process through interactions with Yap1.

Actin and Src-family kinases regulate nuclear YAP1 and its export

This study identifies mechanisms regulating YAP1 nuclear shuttling in fibroblasts, showing that Src and actomyosin suppress YAP1 export, and nuclear export is central to YAP1 regulation.

Epidermal YAP Activity Drives Canonical WNT16/β-catenin Signaling to Promote Keratinocyte Proliferation in vitro and in the Murine Skin

This study shows that YAP activity drives WNT16/{beta}-catenin signaling to promote keratinocyte proliferation in murine skin, identifying WNT16 as a paracrine ligand in this process.

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

This study shows YAP and TAZ regulate endothelial cell dynamics and vascular development by modulating junctions and signaling pathways.

The Hippo pathway effector Taz is required for cell fate specification and fertilization in zebrafish

This study identifies Taz as essential for micropylar cell specification and micropyle formation in zebrafish through genetic and molecular analysis.

Skeletal Cell YAP And TAZ Redundantly Promote Bone Development By Regulation Of Collagen I Expression And Organization

This study shows YAP and TAZ redundantly promote bone development by regulating collagen I expression and organization through TEAD4 binding.