Author

Eireen Bartels‐Klein

Max Delbrück Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 5 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Organism:zebrafish· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Holger GerhardtiD· 6 shared Anna SzymborskaiD· 4 shared Katja Meier· 4 shared Alexandra Klaus‐BergmanniD· 3 shared Baptiste CoxamiD· 3 shared Irene HollfingeriD· 3 shared Silvanus AltiD· 3 shared André RosaiD· 2 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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6 shared papersDevelopmental Biology

Holger GerhardtORCID

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Author profile →

6 papers

Recent·Most cited

Endothelial YAP/TAZ rewiring under cardiometabolic stress drives sex-divergent vascular remodeling in heart failure with preserved ejection fraction

Alexandra Klaus‐Bergmann, Laura Katharina Sievers, Jakob Versnjak, Katharina Koch, Tomasz J. Nawara, Eireen Bartels‐Klein, Oliver Popp, January Mikolaj Weiner, Katja Meier, Irene Hollfinger, Ilona Kamer, Martin Taube, Arnd Heuser, Tatiana Borodina, Dieter Beule, , Holger Gerhardt

This study identifies endothelial YAP/TAZ signaling as a driver of sex-divergent vascular remodeling in HFpEF, linking cardiometabolic stress to microvascular changes through YAP1 and ESM1.

bioRxiv · May 13, 2026 · PreprintCell Biology

Reconstructing stochastic cell population trajectories reveals regulators and heterogeneity of endothelial flow-migration coupling driving vascular remodelling

Wolfgang Giese, André Rosa, Elisabeth Baumann, Olya Oppenheim, Emir Bora Akmeriç, Santiago Andrade, Irene Hollfinger, Eireen Bartels‐Klein, Silvanus Alt, Holger Gerhardt

The paper develops a computational model to analyze EC migration during vascular remodelling, finding that directional migration is driven by dual force fields and mediated by Cdc42 with cell population heterogeneity.

bioRxiv · May 30, 2023 · PreprintDevelopmental Biology

Svep1 stabilizes developmental vascular anastomosis in reduced flow conditions.

Baptiste Coxam, R Collins, Melina Hußmann, Yvonne Huisman, Katja Meier, Simone Jung, Eireen Bartels‐Klein, Anna Szymborska, Lise Finotto, Christian SM Helker, Didier Y. R. Stainier, Stefan Schulte‐Merker, Holger Gerhardt

This study identifies Svep1 as a factor that stabilizes vascular anastomosis in zebrafish embryos under reduced flow conditions.

Development · Mar 15, 2022Peer-reviewedDevelopmental Biology

Wasp controls oriented migration of endothelial cells to achieve functional vascular patterning

André Rosa, Wolfgang Giese, Katja Meier, Silvanus Alt, Alexandra Klaus‐Bergmann, Lowell T. Edgar, Eireen Bartels‐Klein, R Collins, Anna Szymborska, Baptiste Coxam, Miguel O. Bernabéu, Holger Gerhardt

The paper shows that WASp regulates endothelial cell migration directionality in zebrafish, leading to proper vascular patterning and preventing vascular malformations.

Development · Dec 21, 2021Peer-reviewedDevelopmental Biology

Vasohibin-1 mediated tubulin detyrosination selectively regulates secondary sprouting and lymphangiogenesis in the zebrafish trunk

Marta Bastos Oliveira, Katja Meier, Simone Jung, Eireen Bartels‐Klein, Baptiste Coxam, Ilse Geudens, Anna Szymborska, Renae Skoczylas, Ines Fechner, Katarzyna Koltowska, Holger Gerhardt

This study shows that Vasohibin-1 mediates tubulin detyrosination in zebrafish endothelial cells, selectively regulating secondary sprouting and lymphangiogenesis in the trunk.

Development · Feb 5, 2021Peer-reviewedDevelopmental Biology

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

Filipa Neto, Alexandra Klaus‐Bergmann, Yu Ting Ong, Silvanus Alt, Anne-Clémence Vion, Anna Szymborska, Joana R. Carvalho, Irene Hollfinger, Eireen Bartels‐Klein, Claudio Areias Franco, Michael Potente, Holger Gerhardt

This study shows YAP and TAZ regulate endothelial cell dynamics and vascular development by modulating junctions and signaling pathways.

eLife · Feb 5, 2018Peer-reviewedDevelopmental Biology