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Running with an exotendon reduces compressive knee contact force

This study finds that using an exotendon reduces peak knee compressive contact force during running without affecting shear forces or other joints.

Optimizing C14120-based LNPs for in vitro and in vivo mRNA delivery

This study evaluates C14120-based LNPs for mRNA delivery, showing correlations between lipid composition and transfection efficiency in vitro and organ-specific targeting in vivo.

Virtual Immersion in Biomedical Engineering (VIBE): Exposing undergraduates to culturally sensitive engineering design and professional experiences at scale

VIBE provides a virtual summer program for undergraduates to develop engineering design skills and global awareness through collaborative projects and professional development.

MemPPI platform for measuring and engineering membrane protein-protein interactions in mammalian cells via split nanoluciferase

The paper develops a platform to measure and engineer membrane protein-protein interactions using split nanoluciferase, improving assay accuracy and compatibility with protein engineering.

Gene Delivery Mediated by Backbone-Degradable RAFT Copolymers

This study develops backbone-degradable cationic copolymers for gene delivery, showing improved transfection efficiency without increased cytotoxicity.

Embedding Perfusable Microchannel Networks in Photoclickable Bioresins via High-Resolution Digital Light Processing

This paper develops a biocompatible photoresin for 3D bioprinting perfusable microvascular networks using digital light processing.

High-throughput Genome Wide CRISPR Knock Out mechanical sort identifies genes driving metastatic cancer cell softening

This study uses CRISPR knockout and mechanical sorting to identify genes affecting cell stiffness in ovarian cancer, finding three genes linked to increased stiffness and patient survival.

Refined Myocardium Segmentation from CT Using a Hybrid-Fusion Transformer

This paper presents a Hybrid-Fusion Transformer model that refines myocardium segmentation in cardiac CT by combining CT images with semi-automatic labels to remove papillary muscles.

Decellularized Small Intestine for Full Thickness Burn Wound Treatment

This paper develops a decellularized porcine small intestine scaffold for burn wound treatment, showing good mechanical properties, fluid absorption, and cytocompatibility.

Automated Detection of Quiet and Non-Quiet Sleep in Preterm Neonates from aEEG: Towards Predicting Brain Maturation

This paper develops an automated method to detect quiet and non-quiet sleep in preterm neonates using aEEG, showing strong correlation with brain maturation.

Real-time measurement of short-chain fatty acids via microwave sensing: A pilot study

This paper evaluates microwave sensing to differentiate short-chain fatty acids (SCFAs) and their ratios using dielectric signatures, achieving high accuracy in classification.

In silico model of basal ganglia Deep Brain Stimulation in Parkinsons Disease captures range of effective parameters for pathological beta power suppression

The paper develops a computational model of basal ganglia DBS in Parkinson's disease to identify effective parameters for suppressing pathological beta oscillations.

Paired single-cell imaging of calcium and expression to map niches of identity and function

This paper introduces CARBONITE, a method that links calcium dynamics with molecular markers in single cardiomyocytes, revealing functional and identity heterogeneity.

Exogenous Sphingomyelinase Mediates MSC-derived EV Biogenesis and Enhances Potency via Repackaging of Molecular Cargo

The paper shows that exogenous sphingomyelinase increases MSC-derived EV yield and alters their cargo, enhancing therapeutic effects in a murine wound model.

Towards an AI-based knowledge assistant for goat farmers based on Retrieval-Augmented Generation

This paper develops an AI-based knowledge assistant for goat farmers using Retrieval-Augmented Generation to improve LLM performance on structured knowledge tasks.

Biomechanics of chemically treated hair for continuous 1D strands

This study examines how chemical treatments affect the mechanical properties of human hair strands, finding that NaOH treatment enhances stiffness and strength while preserving extensibility.

A Biomechanical Hand Model to Quantify Finger Joint Kinematics Using a 3D Motion Capture System

The paper analyzes finger joint kinematics using a biomechanical hand model and motion capture, finding task type primarily affects movement metrics while frequency impacts speed and harmonic distortion.

The Electromagnetic-Core-First Paradigm: A Mechatronic Co-Design Framework for High-Density Implantable Systems

This paper introduces the Electromagnetic Core-First framework to resolve design conflicts in implantable mechatronic systems, achieving high performance and biocompatibility in a miniaturized blood pump.

Integration and harmonization of cell shape images for generative modeling

This paper harmonizes 2D and 3D immunofluorescent cell shape datasets using generative AI to create synthetic cells for machine learning and in silico studies.

PiggyBac mediated transgenesis and CRISPR/Cas9 knockout in the greater waxmoth, Galleria mellonella

This study develops genetic tools for Galleria mellonella, enabling transgenesis via PiggyBac and CRISPR/Cas9 gene knockout, enhancing its use as an infection model.