Stefan Redl

Quality control at the Golgi couples membrane proteostasis to lipid metabolism

The paper identifies a Golgi quality control checkpoint in yeast that links membrane proteostasis to lipid metabolism, showing that lipid imbalance from proteostasis defects is lethal.

Ultrastructure of stemness and differentiated state in Hydra epithelial cells

The paper uses electron microscopy to compare stem-like and differentiated states in Hydra epithelial cells, revealing distinct ultrastructural features that challenge the traditional separation of stem and differentiated cells.

Structural assembly of the glycan-rich, chitin-reinforced adhesive of Hydra is coordinated by a lectin-like protein, HvAb1

This study identifies HvAb1 as a lectin-like protein organizing a glycan-rich, chitin-reinforced adhesive in Hydra, enabling reversible underwater adhesion.

Ex Vivo Assay for Organ-Specific Cancer Cell Invasion

This paper develops an ex vivo model using organ-derived ECM scaffolds to study cancer cell invasion, showing organ-specific invasion patterns that match clinical observations.

Molecular dynamics of the matrisome across sea anemone life history

The paper identifies conserved matrisomal networks in sea anemones that coordinate life history transitions through proteomic and transcriptomic analysis.

Extensive nuclear gyration and pervasive non-genic transcription during primordial germ cell development in zebrafish

The paper investigates post-migratory zebrafish primordial germ cells, finding delayed gene activation, nuclear gyration, and piRNA pathway activation without nuclear Piwi proteins.

Tdrd6a regulates the aggregation of Buc into functional subcellular compartments that drive germ cell specification

This study identifies Tdrd6a as a regulator of Buc protein aggregation, which is essential for forming subcellular compartments that drive germ cell specification in zebrafish.

GTSF-1 is required for the formation of a functional RNA-dependent RNA Polymerase complex in C. elegans

The paper identifies GTSF-1 as a protein required for the formation of an RNA-dependent RNA Polymerase complex in C. elegans, which is essential for 26G-RNA generation.

Super-resolution imaging reveals structurally distinct periodic patterns of chromatin along pachytene chromosomes

The paper uses super-resolution imaging to reveal periodic chromatin patterns on pachytene chromosomes in mouse oocytes, showing structured distributions of repressive and active histone marks.