C. Li

The paper introduces a method to continuously monitor Masson pine seedling quality by measuring root elongation rate using statistical interferometry.

This study identifies spliced peptides and cytokine-driven changes in the immunopeptidome of melanoma, showing conserved immunogenic peptides across patients.

This study identifies amlodipine as a drug that reduces PD-L1 expression and enhances antitumor immunity by blocking calcium flux and autophagic degradation of PD-L1.

This study identifies the molecular mechanism by which CheY-P controls rotational switching of the bacterial flagellar motor in Borrelia burgdorferi by interacting with FliM and remodeling FliG2.

This study shows H-NS alleviates envelope stress from MBL expression and DNA-damaging agents in A. baumannii, linking it to stress response and carbapenem resistance.

This study uses FAST, a chemogenetic fluorescent reporter, to visualize exported bacterial proteins in live imaging, demonstrating its functionality on both diderm and monoderm bacteria.

The paper presents the crystal structure of SARS-CoV-2 main protease covalently bound to a metabolite of HEAT, revealing a pro-drug mechanism and potential for non-peptidic inhibitors.

The paper shows that PPD1 has a stronger effect on wheat heading time than CO1 and CO2, and that these genes can function independently in photoperiodic responses.

The paper identifies and analyzes MATE transporter genes in wild chickpea species under aluminum stress, finding that CaMATE2 is upregulated in all lines while CaMATE1 is upregulated in most, correlating with root growth responses.

The paper shows that monounsaturated fatty acids (MUFA) are essential for B cell function and humoral immunity, with SCD-mediated MUFA production supporting early B cell development and germinal center formation.

The paper uses a HOXA9-mCherry reporter and CRISPR/Cas9 screens to identify USF1/USF2 as regulators of HOXA9 in MLLr leukemia, showing their role in leukemia cell proliferation.

A purified inactivated SARS-CoV-2 vaccine candidate (PiCoVacc) induces neutralizing antibodies in animals and shows safety and partial to complete protection against SARS-CoV-2 strains.

The paper investigates how HetR controls gene expression from DIF1 motif promoters during heterocyst differentiation, showing dependence on HetZ and modulation by PatU3.

This study shows that Scutellaria baicalensis extract and its compound baicalein inhibit SARS-CoV-2 replication and 3CLpro activity in vitro.

The paper analyzes SARS-CoV-2 mutation dynamics, showing lower mutation rates than SARS and identifying an ACE2-binding affinity-reducing RBD mutation from an Indian sample collected in January 2020.

The study shows that organic manure and rice straw residue increase soil microbial diversity and abundance in double-cropping paddy fields compared to chemical fertilizer alone or no fertilizer.

This study identifies a regulatory mechanism where coupled Ca2+-regulatory mechanisms on both sides of the mitochondrial inner membrane control MCU-mediated Ca2+ uptake.

The paper investigates SARS-CoV-2 infection in cats by detecting serum antibodies, finding 14.7% of post-outbreak samples positive for RBD and 11 with neutralizing antibodies.

This paper develops fully human single-domain antibodies against SARS-CoV-2 and identifies their neutralizing activity and immunogenic profile compared to SARS-CoV and MERS-CoV.

This paper introduces an ultrasensitive fluorogenic probe for detecting human heparanase activity with a picomolar detection limit and demonstrates its use in high-throughput inhibitor screening.

This study designs, synthesizes, and evaluates two peptidomimetic aldehydes as antiviral drug candidates targeting SARS-CoV-2 main protease, showing potent inhibition and anti-infection activity.

This study shows that FcRn, not FcγRs, is responsible for maternal-fetal transport of IgG antibodies, suggesting FcRn engineering could improve antibody transfer to the fetus.

OsFIT interacts with OsIRO2 to enhance its nuclear accumulation and activate Fe-uptake gene expression in rice.

This study investigates how white leaves in Actinidia kolomikta attract pollinators and maintain photosynthetic capacity, enhancing reproductive fitness through dual functions.

The paper uses a within-host viral dynamic model to estimate the basic reproductive numbers of SARS-CoV-2 and MERS-CoV using chest radiograph data.

The paper identifies a ciliary tip signaling compartment formed by intraflagellar transport and shows it is essential for salt detection in C. elegans.

The paper investigates the genetic basis of rumen evolution by comparing transcriptomes and genomic data across ruminants, camels, and cetaceans, identifying key genetic innovations.

The paper presents seven new exon probe sets and a bioinformatics pipeline for fish phylogenomics, enabling accurate phylogenetic analysis by filtering paralogs and integrating old and new data.

This study shows that the SARS-CoV-specific antibody CR3022 binds strongly to 2019-nCoV RBD with a KD of 6.3 nM, while other antibodies targeting the ACE2 site fail to bind, highlighting the importance of RBD differences for cross-reactivity.

This study profiles microbial activities in deep sea cold seep sediments, revealing hydrocarbon oxidation pathways and their role in sustaining diverse microbial communities across redox gradients.