Author

H. D. Mitchell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Plant Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:Arabidopsis· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

L. M. Markillie· 4 shared K. M. Waters· 3 shared R. S. Baric· 3 shared A. C. Sims· 2 shared E. T. McAnarney· 2 shared S. R. Leist· 2 shared V. D. Menachery· 2 shared A. H. Ahkami· 1 shared

Activity by Year

2017-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersPlant Biology

L. M. Markillie

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Single-cell proteomics of Arabidopsis leaf mesophyll identifies drought stress-related proteins

J. M. Fulcher, P. Dawar, V. K. Balasubramanian, S. M. Williams, K. Nadeau, T. E. Winkler, L. M. Markillie, H. D. Mitchell, A. H. Ahkami, L. Pasa-Tolic, Y. Zhu

This study applies single-cell proteomics to Arabidopsis leaf mesophyll cells to identify drought stress-related proteins and changes in protein networks.

bioRxiv · Jul 1, 2024 · PreprintPlant Biology

Oligosaccharide production and signaling correlate with delayed flowering in an Arabidopsis genotype grown and selected in high

H. Kinmonth-Schultz, S. M. Walker, K. Bingol, D. W. Hoyt, Y.-M. Kim, L. M. Markillie, H. D. Mitchell, C. D. Nicora, R. Taylor, J. K. Ward

This study compares metabolomic and transcriptomic changes in two Arabidopsis genotypes under elevated CO2, finding that SG delays flowering due to higher oligosaccharide production and altered carbohydrate metabolism.

bioRxiv · Jun 19, 2023Plant Biology

A crucial role for dynamic expression of components encoding the negative arm of the circadian clock

B. Wang, X. Zhou, A. N. Kettenbach, H. D. Mitchell, L. M. Markillie, J. J. Loros, J. C. Dunlap

This study identifies brd-8 as a circadian-regulated component of the NuA4 histone acetyltransferase complex that modulates frq expression and circadian rhythm in Neurospora.

bioRxiv · Apr 24, 2023Biochemistry

The stem cell-type transcriptome of bioenergy sorghum reveals the spatial regulation of secondary cell wall networks

J. Fu, B. McKinley, B. James, W. Chrisler, L. M. Markillie, M. J. Gaffrey, H. D. Mitchell, G. Orr, K. Swaminathan, J. Mullet, A. Marshall-Colon

The paper identifies cell-type specific gene expression and regulatory networks in bioenergy sorghum stems to enable engineering for biofuel production.

bioRxiv · Apr 22, 2023 · PreprintPlant Biology

Host network-based discovery of critical regulators of innate immunity, virus growth, and pathogenesis in influenza virus infection

A. J. Eisfeld, S. Fan, H. Rao, B. A. Venkatachalam, D. W. Smith, P. J. Halfmann, K. B. Walters, S. Nair, L. B. Thackray, J. F. Kocher, A. C. Sims, H. D. Mitchell, G. Neumann, V. Blank, K. M. Waters, , Y. Kawaoka

The paper identifies novel innate immune regulators affecting influenza virus replication and pathogenesis through experimental validation of network model predictions.

bioRxiv · Aug 29, 2022 · PreprintMicrobiology

Combination attenuation offers strategy for live-attenuated coronavirus vaccines

V. D. Menachery, L. Gralinski, H. D. Mitchell, K. Dinnon, S. R. Leist, B. Yount, E. T. McAnarney, R. Graham, K. M. Waters, R. S. Baric

This study shows combining NSP16 mutation with other attenuating mutations creates a safe and effective live-attenuated coronavirus vaccine that works in aged mice and against heterologous challenges.

bioRxiv · Apr 28, 2018Microbiology

MERS-CoV NSP16 necessary for IFN resistance and viral pathogenesis

V. D. Menachery, L. E. Gralinski, H. D. Mitchell, K. H. Dinnon, S. R. Leist, B. L. Yount, R. L. Graham, E. T. McAnarney, K. G. Stratton, A. S. Cockrell, K. Debbink, A. C. Sims, K. M. Waters, R. S. Baric

This study shows that disrupting MERS-CoV NSP16's 2O methyl-transferase activity attenuates viral pathogenesis and provides a live attenuated vaccine platform.

bioRxiv · Aug 8, 2017Microbiology