Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
B. Ying, C.-Y. Liang, P. Desai, S. Scheaffer, S. Elbashir, D. K. Edwards, L. B. Thackray, M. S. Diamond
This study shows that boosting mice with mRNA vaccines in the ipsilateral or contralateral arm leads to equivalent immune responses and protection against SARS-CoV-2 Omicron.
Journal of Virology · Sep 17, 2024Peer-reviewedMicrobiology
T. A. Desautels, K. T. Arrildt, A. T. Zemla, E. Y. Lau, F. Zhu, D. Ricci, S. Cronin, S. Zost, E. Binshtein, S. M. Scheaffer, B. Dadonaite, B. K. Petersen, T. B. Engdahl, E. Chen, L. S. Handal, , Carnahan
This paper computationally redesigns an antibody to restore potency against SARS-CoV-2 Omicron subvariants while maintaining efficacy against Delta and other variants.
Nature · May 8, 2024Peer-reviewedMicrobiology
P. Desai, C. E. Karl, B. Ying, C.-Y. Liang, T. Garcia-Salum, A. C. Santana, F. T. Caten, J. F. Urban, S. M. Elbashir, D. K. Edwards, S. P. Ribeiro, L. B. Thackray, R.-P. K. Sekaly, M. S. Diamond
This study shows that intestinal helminth infection reduces T cell responses to an mRNA SARS-CoV-2 vaccine and weakens protection against Omicron but not the ancestral strain.
bioRxiv · Jan 14, 2024 · PreprintImmunology
G. Stewart-Jones, S. M. Elbashir, K. Wu, D. Lee, I. Renzi, B. Ying, M. Koch, C. E. Sein, A. Choi, B. Whitener, D. Garcia-Dominguez, C. Henry, A. Woods, L. Ma, D. Montes Berrueta, , A. Carfi
The paper develops and evaluates an mRNA vaccine, mRNA-1283, encoding SARS-CoV-2 spike N-terminal and receptor-binding domains, showing improved immunogenicity and protection against multiple variants in mice.
bioRxiv · Oct 7, 2022 · PreprintImmunology
S. M. Scheaffer, D. Lee, B. Whitener, B. Ying, K. Wu, H. Jani, P. Martin, N. J. Amato, L. E. Avena, D. M. Berrueta, S. D. Schmidt, S. O'Dell, A. Nasir, G.-Y. Chuang, G. Stewart-Jones, , M. S. Diamond
This study evaluates bivalent SARS-CoV-2 mRNA vaccines and finds they induce broader neutralizing antibodies and better protection against BA.5 Omicron compared to monovalent vaccines.
bioRxiv · Sep 12, 2022 · PreprintMicrobiology
A. J. Eisfeld, S. Fan, H. Rao, B. A. Venkatachalam, D. W. Smith, P. J. Halfmann, K. B. Walters, S. Nair, L. B. Thackray, J. F. Kocher, A. C. Sims, H. D. Mitchell, G. Neumann, V. Blank, K. M. Waters, , Y. Kawaoka
The paper identifies novel innate immune regulators affecting influenza virus replication and pathogenesis through experimental validation of network model predictions.
bioRxiv · Aug 29, 2022 · PreprintMicrobiology
B. Ying, S. M. Scheaffer, B. Whitener, C.-Y. Liang, O. Dmytrenko, S. Mackin, K. Wu, D. Lee, L. E. Avena, Z. Chong, J. B. Case, L. Ma, T. Kim, C. Sein, A. Woods, , M. S. Diamond
This study shows that boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibodies and protection against B.1.1.529 in mice, with the Omicron-matched booster showing slightly better outcomes.
bioRxiv · Feb 7, 2022 · PreprintMicrobiology
B. Ying, B. Whitener, L. A. VanBlargan, A. O. Hassan, S. Shrihari, C.-Y. Liang, C. E. Karl, S. Mackin, R. E. Chen, N. M. Kafai, S. H. Wilks, D. J. Smith, J. M. Carreno, G. Singh, F. Krammer, , M. S. Diamond
This study evaluates the protective efficacy of mRNA vaccines against SARS-CoV-2 variants in mice, showing that low-dose vaccines lead to breakthrough infections with Delta variant.
bioRxiv · Aug 25, 2021Microbiology
D. M. Alvarado, J. Son, L. B. Thackray, M. Diamond, S. Ding, M. A. Ciorba, Washington University IBD Investigators Group
This study investigates whether mesalamine affects SARS-CoV-2 infection and disease severity in mice and human intestinal cells, finding no change in viral levels but reduced ACE2 expression.
bioRxiv · Jul 23, 2021Microbiology
A. Schafer, L. E. Gralinski, S. R. Leist, E. S. Winkler, B. K. Hampton, M. A. Mooney, K. L. Jensen, R. L. Graham, S. Agnihothram, S. Jeng, S. Chamberlin, T. A. Bell, D. T. Scobey, L. A. VanBlargan, L. B. Thackray, , R. S. Baric
The paper identifies host susceptibility loci for SARS-CoV and SARS-CoV-2 using GWAS and Collaborative Cross datasets, validating CCR9 as a key regulator of severe disease outcomes across species.
bioRxiv · May 14, 2021 · PreprintMicrobiology
S. J. Zost, P. Gilchuk, J. B. Case, E. Binshtein, R. E. Chen, J. X. Reidy, A. Trivette, R. S. Nargi, R. E. Sutton, N. Suryadevara, L. E. Williamson, E. C. Chen, T. Jones, S. Day, L. Myers, , J. E. Crowe
The paper identifies potent neutralizing antibodies against SARS-CoV-2 that block receptor binding and protect animals, providing insights for vaccine and therapy development.
bioRxiv · May 22, 2020Immunology