Author

Jason T. Gatlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jonathan D. FinniD· 3 shared Sandeep KumariD· 3 shared Brett EstesiD· 2 shared Connor McGinnis· 2 shared Dane Z. HazelbakeriD· 2 shared Daniel J. O’ConnelliD· 2 shared Davood NorouziiD· 2 shared Jenny XieiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioengineering

Jonathan D. FinnORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Highly Efficient Multiplexed Genome Engineering and Clone Selection to Enable Next Generation Induced Pluripotent Stem Cell (iPSC)-based Cell Therapies

Kaivalya Molugu, Ruba Halaoui, Mohammed Zeaiter, Anne M. Bara, Matthew H. Bakalar, Bruna Castro de Oliveira, Connor McGinnis, Jie Wang, Marie-Joe Kimaz, Lauren Herchenroder, Arun Bhattathiri, Alexander Allen, Minggang Fang, Davood Norouzi, Didac Santesmasses, , Chong T. Luo

This paper introduces a novel genome engineering method for iPSCs that enables efficient multiplex gene editing and clone selection, improving the precision and speed of iPSC-based therapies.

bioRxiv · Dec 25, 2025 · PreprintGenomics

Ligase-mediated programmable genomic integration (L-PGI): an efficient site-specific gene editing system that overcomes the limitations of reverse transcriptase-based editing systems

Angela X. Nan, Michael Chickering, Christopher L. Bartolome, Neeta Shadija, Dan Li, Brett Estes, Jessica R. Von Stetina, Wei Li, Jason L. Andresen, Kaivalya Molugu, Ravindra Amunugama, Minggang Fang, Chen Bai, Jie Wang, Davood Norouzi, , Jenny Xie

This paper introduces L-PGI, a ligase-mediated gene editing system that enables efficient and precise genomic integration in both dividing and nondividing cells, overcoming limitations of reverse transcriptase-based methods.

Nature Communications · Dec 10, 2025Peer-reviewedBioengineering

Curative levels of endogenous gene replacement achieved in non-human primate liver using programmable genomic integration

Jenny Xie, Maike Thamsen Dunyak, Patrick Hanna, Angela Xinyi Nan, Brett Estes, Jesse C. Cochrane, Shuai Wu, Jie Wang, Connor McGinnis, Qiang Wang, Rejina Pokharel, Dev Paudel, Jason Zhang, Dan Li, Parth H. Amin, , Jonathan D. Finn

This paper demonstrates programmable genomic integration in non-human primate liver, achieving curative levels of gene expression in over 50% of liver cells.

bioRxiv · Oct 12, 2024 · PreprintBioengineering