K. Kim

This study shows that acetylation of H2B.Z is critical for Toxoplasma gondii's growth, differentiation, and virulence.

This study identifies small molecule activators of NAPE-PLD that enhance efferocytosis by macrophages, suggesting their potential therapeutic use in cardiometabolic diseases.

This paper develops a machine vision-based tool to assess pain and analgesia in mice, outperforming traditional methods and enabling high-throughput analysis.

This study identifies and characterizes enzymes involved in the biosynthesis of kratom opioids, showing their promiscuity for producing derivatives in heterologous systems.

The paper identifies clonally expanded CD8+ T cells driven by IL21 in ICI-thyroiditis using scRNA-seq and validates their role in thyroid inflammation.

The paper maps single-cell lysis probabilities to population-level biomass dynamics during antibiotic treatment, showing how filamentation extent influences lysis and validates this with experiments.

This study shows that Shigella IpaH9.8 inhibits GBP1-dependent LPS release from intracellular bacteria, preventing caspase-4 activation and pyroptosis.

This study examines how liver and brain cells use autophagy under normal and nutrient-deprived conditions, revealing tissue-specific differences in organelle turnover and cargo capture.

This study shows that the prismatic layer of Pinna nobilis shells functions as light guides, enhancing optical resolution and contrast for tracking movement.

This paper identifies a small molecule, ARM-1, that inhibits bacterial evolution by targeting Mfd, delaying AMR development across multiple pathogens.

This paper identifies small RNAs that regulate Salmonella virulence gene expression by modulating hilD mRNA stability through its 3' UTR.

This study shows that IGF-1 therapy increases muscle size and strength in a rodent PAD model, with greater effects in female mice.

This study shows that dantrolene reduces ventricular tachycardia, fibrosis, and improves cardiac function in a mouse model of chronic ischemic heart disease.

This study identifies Prdx5's role in bone regeneration by regulating osteoblast differentiation through interaction with hnRNPK, impacting osteocalcin expression and osteoclast activity.

This study shows that glioblastoma cells use autophagosomes in migrasomes to relieve stress and prevent cell death by inhibiting autophagosome/lysosome fusion.

The paper shows that low dietary fiber promotes colitis in genetically susceptible mice by eroding mucus, while a fiber-free diet increases anti-inflammatory metabolites, highlighting microbial function over taxa in IBD regulation.

This study identifies AAT binding to the glucocorticoid receptor in macrophages, showing its role in anti-inflammatory and host-defense functions.

This study identifies Anoctamin 9 as essential for mammalian olfaction, showing its role in amplifying olfactory signals and linking its downregulation to Covid-19-associated anosmia.

This study presents structures of the human erythrocyte ankyrin-1 complex, revealing its architecture and interactions with membrane proteins.

This study investigates how adipocyte shape, size, and lipid accumulation affect mechanical properties of adipose tissue in health, obesity, and diabetes.

This study identifies lncRNA152 as an angiogenesis-inhibiting tumor suppressor in TNBC that upregulates RBM47, reducing cancer aggressiveness.

This study shows that cigarette smoke-exposed T regulatory cells impair macrophage control of Mycobacterium tuberculosis infection in vitro and in vivo.

The paper shows host APOBEC3A, APOBEC1, and APOBEC3G edit SARS-CoV-2 RNA, promoting viral replication and suggesting APOBEC-mediated mutations contribute to viral evolution and new strain emergence.

This study shows cigarette smoke causes lung lymphatic thrombosis and dysfunction in mice and humans, linking it to emphysema pathogenesis.

This study investigates the thermal behavior of FGF21 and designs a variant with enhanced therapeutic potency through structural analysis and mutagenesis.

The paper introduces a multi-camera array microscope (MCAM) that enables high-resolution, multi-scale imaging of behavior and neural activity in model organisms.

This study investigates how genome divergence and compatibility contribute to the stabilization of hybrid genomes in an allopolyploid plant species.

This study evaluates stress levels in mice across different breeding environments, finding lower cortisol and higher body weight in individually ventilated cages with environmental enrichment.

This study investigates mCRP deposition in AAA and identifies associated proteomic changes and enriched pathways.

This paper develops a framework for rapid bacterial species identification using 3D quantitative phase imaging and artificial neural networks, achieving 99.9% accuracy with single colony-forming units.