Author

Magali Tichit

Institut Pasteur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Genomics· 1 Immunology· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 5 Research Focus:host-pathogen & immune response· 4 Assay:bulk RNA-seq· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:database / resource· 1

Frequent Co-Authors

David HardyiD· 5 shared Florence LarrousiD· 3 shared Guilherme Dias de MeloiD· 3 shared Hervé BourhyiD· 3 shared Lauriane KergoatiD· 3 shared Anthony ColéoniD· 2 shared Étienne KornobisiD· 2 shared Flavio AlvareziD· 2 shared

Activity by Year

2018-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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Curved chords = mutual co-authorship

5 shared papersPathology

David HardyORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Improved Immune Responses and Tuberculosis Protection by Aerosol Vaccination with recombinant BCG expressing ESX-1 from Mycobacterium marinum

Fadel Sayes, Wafa Frigui, Alexandre Pawlik, Cécile Tillier, Magali Tichit, David Hardy, Roland Brosch

This study compares aerosol and subcutaneous vaccination with BCG and BCG::ESX-1Mmar, finding aerosol vaccination enhances immune responses and protection against tuberculosis in mice.

PLoS Pathogens · Feb 23, 2026Peer-reviewedMicrobiology

Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem

Anthony Coléon, Florence Larrous, Lauriane Kergoat, Magali Tichit, David Hardy, Thomas Obadia, Étienne Kornobis, Hervé Bourhy, Guilherme Dias de Melo

This study shows that SARS-CoV-2 infects and persists in hamster brainstem, causing neurodegenerative and immunometabolic changes linked to neuropsychiatric and cognitive symptoms.

Nature Communications · Jul 22, 2025Peer-reviewedPathology

The SARS-CoV-2 envelope PDZ Binding Motif acts as a virulence factor disrupting host's epithelial cell-cell junctions

Flavio Alvarez, Guilherme Dias de Melo, Florence Larrous, Lauriane Kergoat, Batiste Boëda, Vincent Michel, Danielle Seilhean, Magali Tichit, David Hing, David Hardy, Étienne Kornobis, Hervé Bourhy, Nicolas Wolff, Célia Caillet‐Saguy

This study shows that the SARS-CoV-2 E protein's PDZ-binding motif enhances virulence by disrupting epithelial barriers and inflammation, but not neuroinvasion.

Cellular & Molecular Biology Letters · Jul 11, 2025Peer-reviewedPathology

Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosis

Stylianos Papadopoulos, David Hardy, Frédérique Vernel-Pauillac, Magali Tichit, Ivo Gomperts Boneca, Catherine Werts

This study identifies myocarditis and neutrophil-mediated vascular leakage as key factors in fatal murine leptospirosis, distinct from cytokine storm or organ failure.

EBioMedicine · Jan 29, 2025Peer-reviewedImmunology

Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants

Guilherme Dias de Melo, Victoire Perraud, Flavio Alvarez, Alba Vieites Prado, Seonhee Kim, Lauriane Kergoat, Anthony Coléon, Bettina Salome Trüeb, Magali Tichit, Aurèle Piazza, Agnès Thierry, David Hardy, Nicolas Wolff, Sandie Munier, Romain Koszul, , Hervé Bourhy

The paper investigates whether neuroinvasion and anosmia are independent outcomes of SARS-CoV-2 infection by analyzing clinical, olfactory, and neuroinflammatory responses in infected golden hamsters.

Nature Communications · Jul 26, 2023Peer-reviewedNeuroscience

Generating genomic platforms to study Candida albicans pathogenesis

Mélanie Legrand, Sophie Bachellier‐Bassi, Keunsook K. Lee, Yogesh Chaudhari, Hélène Tournu, Laurence Arbogast, Hélène Boyer, Murielle Chauvel, Vitor Cabral, Corinne Maufrais, Audrey Nesseir, Irena Maslanka, Emmanuelle Permal, Tristan Rossignol, Louise A. Walker, , Christophe d’Enfert

The paper generates an ORFeome collection and associated tools for studying Candida albicans pathogenesis.

Nucleic Acids Research · Jun 25, 2018Peer-reviewedGenomics